Cardiac Marker Changes Over Time 

Updated: Nov 20, 2014
  • Author: Buck Christensen; Chief Editor: Buck Christensen  more...
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Cardiac Marker Changes

Cardiac markers are used in the diagnosis and risk stratification of patients with chest pain and suspected acute coronary syndrome (ACS). The cardiac troponins, in particular, have become the cardiac markers of choice for patients with ACS. Cardiac troponin is central to the definition of acute myocardial infarction (MI) in the consensus guidelines from the European Society of Cardiology (ESC) and the American College of Cardiology (ACC). [1, 2, 3]

For a more comprehensive discussion of cardiac markers, see the Medscape article Cardiac Markers.

Table 1. Cardiac Marker Changes Over Time (Open Table in a new window)

Marker Onset (hours) Peak (hours) Duration
Troponin I 3-12 10-24 3-10 days
Troponin T 3-12 12-48 5-14 days
Creatine kinase-MB (CK-MB) 4-6 24 2-3 days
Myoglobin 2-4 6-12 24-36 hours