International Normalized Ratio (INR) Targets: Ischemic Stroke 

Updated: Oct 26, 2021
Author: Buck Christensen; Chief Editor: Buck Christensen 

International Normalized Ratio (INR) Targets: Ischemic Stroke

The international normalized ratio (INR) recommendations below are per guidelines from the American College of Chest Physicians (2008).[1, 2]

Cerebrovascular event

For cerebrovascular event, the recommendations are as follows:

  • INR target (range)

    • Atrial fibrillation (AF) plus ischemic stroke or transient ischemic attack (TIA): 2.5 (2.0-3.0)[3, 4, 5, 6, 7]

    • Venous sinus thrombosis: 2.5 (2.0-3.0)

  • Duration of therapy: Long-term

    • AF plus ischemic stroke or TIA: Long-term

    • Venous sinus thrombosis: 12 months