Psoriatic Arthritis Questions & Answers

Updated: Jul 15, 2020
  • Author: Anwar Al Hammadi, MD, FRCPC; Chief Editor: Herbert S Diamond, MD  more...
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Questions & Answers

Overview

What is psoriatic arthritis?

What are the signs and symptoms of psoriatic arthritis?

Which physical findings are characteristic of psoriatic arthritis?

Which nail changes suggest psoriatic arthritis?

Which extra-articular features may be present in psoriatic arthritis?

What are the patterns of arthritic involvement in psoriatic arthritis?

What is the Classification Criteria for Psoriatic Arthritis (CASPAR)?

What is the role of lab testing in the diagnosis of psoriatic arthritis?

Which radiographic findings suggest psoriatic arthritis?

Which MRI findings suggest psoriatic arthritis?

How is psoriatic arthritis treated?

What is the role of surgery in the treatment of psoriatic arthritis?

What is the role of physical therapy in the treatment of psoriatic arthritis?

What is psoriatic arthritis?

What are the patterns of arthritic involvement in psoriatic arthritis?

What is the asymmetrical oligoarticular arthritis pattern of psoriatic arthritis?

What is the symmetrical polyarthritis pattern of psoriatic arthritis?

What is the distal interphalangeal arthropathy pattern of psoriatic arthritis?

What is the arthritis mutilans pattern of psoriatic arthritis?

What is the spondylitis and sacroiliitis pattern of psoriatic arthritis?

What is synovitis, acne, pustulosis, hyperostosis, and osteitis (SAPHO) syndrome?

What is juvenile psoriatic arthritis?

What is the Classification Criteria for Psoriatic Arthritis (CASPAR)?

What causes psoriatic arthritis?

What is the role of genetics in the pathogenesis of psoriatic arthritis?

What is the role of immunologic factors in the pathogenesis of psoriatic arthritis?

What is the role of environmental factors in the etiology of psoriatic arthritis?

What is the prevalence of psoriatic arthritis in the US?

What is the global prevalence of psoriatic arthritis?

What are baseline variables associated with the development of psoriatic arthritis in multivariate analysis?

What are the racial predilections of psoriatic arthritis?

Which age groups have the highest prevalence of psoriatic arthritis?

What are the sexual predilections of psoriatic arthritis?

What is the prognosis of psoriatic arthritis?

What should be included in patient education about psoriatic arthritis?

Presentation

Which clinical history findings are characteristic of psoriatic arthritis?

What are the symptoms of the preclinical phase of psoriatic arthritis?

Which physical findings are characteristic of psoriatic arthritis?

How are skin lesions characterized in psoriatic arthritis?

Which nail changes are characteristic of psoriatic arthritis?

What are the extra-articular signs and symptoms of psoriatic arthritis?

DDX

Which conditions should be included in the differential diagnosis of psoriatic arthritis?

What are the differential diagnoses for Psoriatic Arthritis?

Workup

What is the role of lab testing in the workup of psoriatic arthritis?

What is the role of erythrocyte sedimentation rate in the workup of psoriatic arthritis?

What is the role of rheumatoid factor testing in the workup of psoriatic arthritis?

What is the role of antinuclear antibodies testing in the workup of psoriatic arthritis?

What is the role of immunoglobulin testing in the workup of psoriatic arthritis?

What is the role of synovial fluid measurement in the workup of psoriatic arthritis?

How is psoriatic arthritis differentiated from RA based on lab findings?

Which histologic findings are characteristic of psoriatic arthritis?

What is the role of imaging studies in the workup of psoriatic arthritis?

Which radiographic findings suggest psoriatic arthritis?

What is the role of CT scanning and MRI in the workup of psoriatic arthritis?

What is the role of ultrasonography in the workup of psoriatic arthritis?

Treatment

How is psoriatic arthritis treated?

How is the severity of psoriatic arthritis and psoriasis is usually assessed?

Which indices are used to measure disease activity and response to treatment in psoriatic arthritis?

Which medications are used in the treatment of psoriatic arthritis?

What is the role of intra-articular injections in the treatment of psoriatic arthritis?

How is severe skin inflammation treated in psoriatic arthritis?

Which biologic agents are used in the treatment of psoriatic arthritis?

What is the role of methotrexate in the treatment of psoriatic arthritis?

What is the efficacy of certolizumab pegol (Cimzia) in the treatment of psoriatic arthritis?

What is the efficacy of golimumab (Simponi Aria) in the treatment of psoriatic arthritis?

What is the efficacy of ustekinumab in the treatment of psoriatic arthritis?

What is the efficacy of secukinumab (Cosentyx) in the treatment of psoriatic arthritis?

What is the efficacy of abatacept (Orencia) in the treatment of psoriatic arthritis?

What is the efficacy of ixekizumab (Taltz) in the treatment of psoriatic arthritis?

What is the efficacy of tofacitinib in the treatment of psoriatic arthritis?

What is the efficacy of apremilast (Otezla) in the treatment of psoriatic arthritis?

What is the role of intramuscular alefacept in the treatment of psoriatic arthritis?

What is the role of sulfasalazine and cyclosporine in the treatment of psoriatic arthritis?

Which drugs have unproven efficacy in the treatment of psoriatic arthritis?

What is the role of dietary modifications in the treatment of psoriatic arthritis?

What is the role of antimalarials in the treatment of psoriatic arthritis?

What is the role of oral corticosteroids in the treatment of psoriatic arthritis?

What are the ACR/NPF guidelines on the nonpharmacologic treatment of psoriatic arthritis?

What is the role of physical therapy in the treatment of psoriatic arthritis?

What is the role of surgery in the treatment of psoriatic arthritis?

Which specialist consultations are beneficial to patients with psoriatic arthritis?

How are exacerbations of psoriatic arthritis prevented?

What are the complications and comorbidities associated with psoriatic arthritis?

Guidelines

Which organizations have issued guidelines on psoriatic arthritis?

What are the EULAR treatment guidelines for psoriatic arthritis?

What are the ACR/NPF guidelines on the treatment of psoriatic arthritis?

What are the AAD treatment guidelines for psoriatic arthritis?

What are BSR treatment guidelines for adult psoriatic arthritis?

What are GRAPPA treatment guidelines for psoriatic arthritis?

Medications

Which medications are used in the treatment of psoriatic arthritis?

Which medications in the drug class CTLA4-Immunoglobulin are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class Interlukin 17 Inhibitors are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class Interlukin 12/23 inhibitors are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class TNF Inhibitors are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class Oral small molecules (OSMs) are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class Nonsteroidal anti-inflammatory drugs (NSAIDs) are used in the treatment of Psoriatic Arthritis?

Which medications in the drug class Janus Kinase (JAK) Inhibitors are used in the treatment of Psoriatic Arthritis?