Gender Dysphoria Differential Diagnoses

Updated: May 09, 2022
  • Author: Mohammed A Memon, MD; Chief Editor: Glen L Xiong, MD  more...
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Diagnostic Considerations

The differential diagnosis should include nonconformity to stereotypical sex role behaviors, transvestic fetishism, gender dysphoria not otherwise specified (with a concurrent congenital intersex condition), and schizophrenia.


Lifetime psychiatric comorbidity in this disorder is high, and this should be taken into account in the assessment and treatment planning of gender dysphoria. Twenty-nine percent of the patients had no concurrent or lifetime-associated disorders; 39% percent fulfilled the criteria for current and 71% for current and/or lifetime-associated disorders. Forty-two percent of the patients were diagnosed with one or more personality disorders. [14]

Differential Diagnoses

  • Body Dysmorphic Disorder

  • Paraphilic Disorder

  • Schizophrenia