Lymphocytic Choriomeningitis Virus (LCMV) Infection Differential Diagnoses

Updated: Sep 11, 2017
  • Author: Philip J McDonald, MD; Chief Editor: Burke A Cunha, MD  more...
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DDx

Diagnostic Considerations

Table 1. Differential Diagnosis of Lymphocytic Choriomeningitis (Open Table in a new window)

Diagnosis

Season

Usual Source

Relative Bradycardia

Pharyngitis

Diarrhea

Parotitis

Orchitis

CSF Glucose level

LCMV infection

Fall/winter

Mouse, hamster

+

+/-

-

+/-

+/-

Normal or decreased

Typhoid fever

Year-round

Food, water

+

+

+ (late)

-

-

Normal

Enteroviral illness

Summer

Water

-

+

+

-

-

Normal

Arboviral illness

Summer

Mosquito

-

-

-

-

-

Normal

Leptospirosis

Summer/fall

Dogs, rats

-

-

-

-

-

Normal

Influenza

Winter

Person

-

+

-

-

-

Normal

Mumps

Winter/spring

Person

-

-

-

+

+/-

Normal or decreased

Including West Nile virus (WNV), Japanese encephalitis virus (JEV), St. Louis encephalitis virus (SLEV), Zika virus (ZIKV), Yellow fever virus (YFV), Western and Eastern equine encephalitis (WEE, EEE)

Other causes of aseptic meningitis (eg, herpes simplex virus (HSV), varicella-zoster virus (VZV), syphilis, Cryptococcus, Coccidioides immitis, Mycobacteria tuberculosis, malignancy, NSAIDs/other medications) should also be considered based on the history.

Differential Diagnoses