Lymphocytic Choriomeningitis Virus (LCMV) Infection Follow-up

Updated: Sep 11, 2017
  • Author: Philip J McDonald, MD; Chief Editor: Burke A Cunha, MD  more...
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Follow-up

Further Inpatient Care

Patients with severe meningoencephalitis are usually hospitalized.

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Deterrence/Prevention

Rodent control measures decrease the frequency of lymphocytic choriomeningitis virus (LCMV) infection. [9]

Laboratory personnel who handle mice or hamsters are at increased risk for LCMV infection. No established method of preventing infection in these situations exists. Prudence dictates the use of gloves when handling these animals, especially if the person's hands are abraded. If the risk of infection is high, consider the use of a personal respirator.

No method is effective to prevent transmission by organ transplantation since determination of pet rodent ownership by the donor is neither sensitive or specific. Testing tissue with RT-PCR and immunohistochemical analysis is extremely expensive and may not necessarily be effective.

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Prognosis

Lymphocytic choriomeningitis (LCM) is rarely fatal; the overall prognosis is excellent.

Patients with encephalitis are at higher risk for neurologic sequelae.

Convalescence may be prolonged, with continuing dizziness, somnolence, and fatigue.

Severe disease leading to death has been reported in immunocompromised patients and organ transplant recipients (7 of 8 infected patients died). [23]

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Patient Education

Avoid exposure to rodent secreta and excreta.

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