Lymphogranuloma Venereum (LGV) Guidelines

Updated: May 15, 2017
  • Author: Pamela Arsove, MD, FACEP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Guidelines

WHO Guidelines on the Treatment of Lymphogranuloma Venereum

WHO recommendations for the treatment of lymphogranuloma venereum (LGV) are as follows: [28]

  • In adults and adolescents with LGV, the guidelines suggest doxycycline 100 mg orally twice daily for 21 days over azithromycin 1 g orally weekly for 3 weeks.
  • Good practice dictates treatment of LGV, particularly for men who have sex with men and for people with HIV infection.
  • When doxycycline is contraindicated, azithromycin should be provided.
  • When neither treatment is available, erythromycin 500 mg orally 4 times a day for 21 days is an alternative.
  • Doxycycline should not be used in pregnant women.