Castleman Disease Differential Diagnoses

Updated: Jul 13, 2017
  • Author: Neetu Radhakrishnan, MD; Chief Editor: Emmanuel C Besa, MD  more...
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DDx

Diagnostic Considerations

The differential diagnoses for the hyaline vascular variant of Castleman disease include the following:

  • Toxoplasma lymphadenitis
  • Burned-out HIV lymphadenitis
  • Follicular hyperplasia of any cause
  • Non-Hodgkin lymphoma subtypes with nodular growth patterns

The differential diagnoses for the plasma cell variant of Castleman disease include the following:

  • Rheumatoid arthritis
  • Plasmacytoma
  • Non-Hodgkin lymphoma subtypes with prominent plasma cells