Pinta Medication

Updated: May 19, 2017
  • Author: Natalie C Klein, MD, PhD; Chief Editor: Mark R Wallace, MD, FACP, FIDSA  more...
  • Print

Medication Summary

The goals of pharmacotherapy are to eradicate the infection, to reduce morbidity, and to prevent complications.



Class Summary

Benzathine penicillin is the DOC but should not be administered to patients who are allergic to penicillin. Alternative therapies include tetracycline or erythromycin.

Penicillin G benzathine (Bicillin LA)

Interferes with cell wall synthesis during active multiplication, resulting in bactericidal activity against susceptible microorganisms. Should not be administered to patients who are allergic to penicillin.

Tetracycline (Achromycin, Sumycin)

Alternative to benzathine penicillin for patients who are allergic to penicillin. Treats gram-positive and gram-negative organisms, as well as mycoplasmal, chlamydial, and rickettsial infections. Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s).

Erythromycin ethylsuccinate (E.E.S., EryPed)

Indicated for the treatment of infections in children who are allergic to penicillin or women who are pregnant. Inhibits bacterial growth, possibly by blocking dissociation of peptidyl tRNA from ribosomes causing RNA-dependent protein synthesis to arrest. In children, age, weight, and severity of infection determine proper dosage. When bid dosing is desired, one half of the total daily dose may be taken q12h. For more severe infections, double the dose.