Pinta Workup

Updated: May 19, 2017
  • Author: Natalie C Klein, MD, PhD; Chief Editor: Mark R Wallace, MD, FACP, FIDSA  more...
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Laboratory Studies

Pinta is most often a clinical diagnosis.

The nontreponemal and treponemal serologic tests used in diagnosing venereal syphilis are used for serodiagnosis of pinta.

Treponemes can be demonstrated by darkfield examination of exudates from early lesions.

Nontreponemal test results (ie, rapid plasma reagent [RPR], Venereal Disease Research Laboratory [VDRL] test) are positive in all stages of pinta except very early lesions. Confirmatory treponemal test results (ie, T pallidum hemagglutination [TPHA], microhemagglutination T pallidum [MHA-TP], fluorescent treponemal antibody absorption [FTA-Abs]) are also positive but are not practical in remote areas.


Histologic Findings

Findings of pinta and yaws are similar, but pinta does not cause ulcer formation. In early lesions, mild acanthosis is present with migration of lymphoid cells into the epidermis. In the late stage, irregular acanthosis or epidermal atrophy occurs. Treponemes can be demonstrated in the epidermis in primary and secondary lesions using silver stain. They are absent in late achromic lesions. [12]