Serratia Treatment & Management

1. Donnenberg MS. Enterobacteriaceae. Mandell GL, Bennett JE, Dolin R, eds. Principles and Practice of Infectious Diseases. 7th. Philadelphia, Pa: Churchill Livingstone - Elsevier; 2010. Vol 2: 2815-2833.

2. Mahlen SD. Serratia infections: from military experiments to current practice. Clin Microbiol Rev. 2011 Oct. 24(4):755-91. [QxMD MEDLINE Link]. [Full Text].

3. Carrero P, Garrote JA, Pacheco S, et al. Report of six cases of human infection by Serratia plymuthica. J Clin Microbiol. 1995 Feb. 33(2):275-6. [QxMD MEDLINE Link].

4. Grohskopf LA, Roth VR, Feikin DR, et al. Serratia liquefaciens bloodstream infections from contamination of epoetin alfa at a hemodialysis center. N Engl J Med. 2001 May 17. 344(20):1491-7. [QxMD MEDLINE Link].

5. Ursua PR, Unzaga MJ, Melero P, et al. Serratia rubidaea as an invasive pathogen. J Clin Microbiol. 1996 Jan. 34(1):216-7. [QxMD MEDLINE Link].

6. Julie G, Julie C, Anne G, Bernard F, Philippe V, Madeleine C, et al. Childhood delayed septic arthritis of the knee caused by Serratia fonticola. Knee. 2009 Dec. 16(6):512-4. [QxMD MEDLINE Link].

7. Elahian F, Moghimi B, Dinmohammadi F, Ghamghami M, Hamidi M, Mirzaei SA. The anticancer agent prodigiosin is not a multidrug resistance protein substrate. DNA Cell Biol. 2013 Mar. 32(3):90-7. [QxMD MEDLINE Link]. [Full Text].

8. Petersen LM, Tisa LS. Friend or foe? A review of the mechanisms that drive Serratia towards diverse lifestyles. Can J Microbiol. 2013 Sep. 59(9):627-40. [QxMD MEDLINE Link].

9. Anonymous. The miracle microbe: Serratia marcescens. [Full Text].

10. Yu VL. Serratia marcescens: historical perspective and clinical review. N Engl J Med. 1979 Apr 19. 300(16):887-93. [QxMD MEDLINE Link].

11. Pérez-Tomás R, Viñas M. New insights on the antitumoral properties of prodiginines. Curr Med Chem. 2010. 17(21):2222-31. [QxMD MEDLINE Link].

12. Chang CC, Chen WC, Ho TF, Wu HS, Wei YH. Development of natural anti-tumor drugs by microorganisms. J Biosci Bioeng. 2011 May. 111(5):501-11. [QxMD MEDLINE Link].

13. Genes C, Baquero E, Echeverri F, Maya JD, Triana O. Mitochondrial dysfunction in Trypanosoma cruzi: the role of Serratia marcescens prodigiosin in the alternative treatment of Chagas disease. Parasit Vectors. 2011 May 6. 4:66. [QxMD MEDLINE Link]. [Full Text].

14. Remuzgo-Martínez S, Aranzamendi-Zaldunbide M, Pilares-Ortega L, Icardo JM, Acosta F, Martínez-Martínez L, et al. Interaction of macrophages with a cytotoxic Serratia liquefaciens human isolate. Microbes Infect. 2013 Jun. 15(6-7):480-90. [QxMD MEDLINE Link].

15. Gupta N, Hocevar SN, Moulton-Meissner HA, Stevens KM, McIntyre MG, Jensen B, et al. Outbreak of Serratia marcescens Bloodstream Infections in Patients Receiving Parenteral Nutrition Prepared by a Compounding Pharmacy. Clin Infect Dis. 2014 Apr 11. [QxMD MEDLINE Link].

16. Ersoz G, Uguz M, Aslan G, Horasan ES, Kaya A. Outbreak of meningitis due to Serratia marcescens after spinal anaesthesia. J Hosp Infect. 2014 Jun. 87(2):122-5. [QxMD MEDLINE Link].

17. Engel HJ, Collignon PJ, Whiting PT, Kennedy KJ. Serratia sp. bacteremia in Canberra, Australia: a population-based study over 10 years. Eur J Clin Microbiol Infect Dis. 2009 Jul. 28(7):821-4. [QxMD MEDLINE Link].

18. Samonis G, Vouloumanou EK, Christofaki M, Dimopoulou D, Maraki S, Triantafyllou E, et al. Serratia infections in a general hospital: characteristics and outcomes. Eur J Clin Microbiol Infect Dis. 2011 May. 30(5):653-60. [QxMD MEDLINE Link].

19. Jones RN. Microbial etiologies of hospital-acquired bacterial pneumonia and ventilator-associated bacterial pneumonia. Clin Infect Dis. 2010 Aug 1. 51 Suppl 1:S81-7. [QxMD MEDLINE Link].

20. Posluszny JA Jr, Conrad P, Halerz M, Shankar R, Gamelli RL. Surgical burn wound infections and their clinical implications. J Burn Care Res. 2011 Mar-Apr. 32(2):324-33. [QxMD MEDLINE Link]. [Full Text].

21. Rastogi V, Purohit P, Peters BP, et al. Pulmonary infection with serratia marcescens. Indian J Med Microbiol. 2002 Jul-Sep. 20(3):167-8. [QxMD MEDLINE Link].

22. Zarogoulidis P, Porpodis K, Konoglou M, Saroglou M, Mitrakas A, Matthaios D, et al. Serratia pneumonia presenting as hemoptysis in a patient with sarcoidosis: a case report. Int J Gen Med. 2011. 4:661-4. [QxMD MEDLINE Link]. [Full Text].

23. Wu YM, Hsu PC, Yang CC, Chang HJ, Ye JJ, Huang CT, et al. Serratia marcescens meningitis: Epidemiology, prognostic factors and treatment outcomes. J Microbiol Immunol Infect. 2012 Aug 24. [QxMD MEDLINE Link].

24. Hiremath S, Biyani M. Technique survival with Serratia peritonitis. Adv Perit Dial. 2006. 22:73-6. [QxMD MEDLINE Link].

25. Friend JC, Hilligoss DM, Marquesen M, Ulrick J, Estwick T, Turner ML, et al. Skin ulcers and disseminated abscesses are characteristic of Serratia marcescens infection in older patients with chronic granulomatous disease. J Allergy Clin Immunol. 2009 Jul. 124(1):164-6. [QxMD MEDLINE Link]. [Full Text].

26. al Hazzaa SA, Tabbara KF, Gammon JA. Pink hypopyon: a sign of Serratia marcescens endophthalmitis. Br J Ophthalmol. 1992 Dec. 76(12):764-5. [QxMD MEDLINE Link].

27. Faro J, Katz A, Berens P, Ross PJ. Premature termination of nursing secondary to Serratia marcescens breast pump contamination. Obstet Gynecol. 2011 Feb. 117(2 Pt 2):485-6. [QxMD MEDLINE Link].

28. Jones J, Crete J, Neumeier R. A case report of pink breast milk. J Obstet Gynecol Neonatal Nurs. 2014 Sep. 43(5):625-30. [QxMD MEDLINE Link].

29. Ostrowsky BE, Whitener C, Bredenberg HK, et al. Serratia marcescens bacteremia traced to an infused narcotic. N Engl J Med. 2002 May 16. 346(20):1529-37. [QxMD MEDLINE Link].

30. Sunenshine RH, Tan ET, Terashita DM, et al. A multistate outbreak of Serratia marcescens bloodstream infection associated with contaminated intravenous magnesium sulfate from a compounding pharmacy. Clin Infect Dis. 2007 Sep 1. 45(5):527-33. [QxMD MEDLINE Link].

31. Horcajada JP, Martinez JA, Alcon A, et al. Acquisition of multidrug-resistant Serratia marcescens by critically ill patients who consumed tap water during receipt of oral medication. Infect Control Hosp Epidemiol. 2006 Jul. 27(7):774-7. [QxMD MEDLINE Link].

32. Mills J, Drew D. Serratia marcescens endocarditis: a regional illness associated with intravenous drug abuse. Ann Intern Med. 1976 Jan. 84(1):29-35. [QxMD MEDLINE Link].

33. Pinna A, Usai D, Sechi LA, Carta A, Zanetti S. Detection of virulence factors in Serratia strains isolated from contact lens-associated corneal ulcers. Acta Ophthalmol. 2011 Jun. 89(4):382-7. [QxMD MEDLINE Link].

34. Friedman ND, Peterson NB, Sumner WT, et al. Spontaneous dermal abscesses and ulcers as a result of Serratia marcescens. J Am Acad Dermatol. 2003 Aug. 49(2 Suppl Case Reports):S193-4. [QxMD MEDLINE Link].

35. Mlynarczyk A, Mlynarczyk G, Pupek J, et al. Serratia marcescens isolated in 2005 from clinical specimens from patients with diminished immunity. Transplant Proc. 2007 Nov. 39(9):2879-82. [QxMD MEDLINE Link].

36. Bertrand X, Dowzicky MJ. Antimicrobial susceptibility among gram-negative isolates collected from intensive care units in North America, Europe, the Asia-Pacific Rim, Latin America, the Middle East, and Africa between 2004 and 2009 as part of the Tigecycline Evaluation and Surveillance Trial. Clin Ther. 2012 Jan. 34(1):124-37. [QxMD MEDLINE Link].

37. Sader HS, Farrell DJ, Flamm RK, Jones RN. Antimicrobial susceptibility of Gram-negative organisms isolated from patients hospitalized in intensive care units in United States and European hospitals (2009-2011). Diagn Microbiol Infect Dis. 2014 Apr. 78(4):443-8. [QxMD MEDLINE Link].

38. Tamma PD, Girdwood SC, Gopaul R, Tekle T, Roberts AA, Harris AD, et al. The use of cefepime for treating AmpC ß-lactamase-producing Enterobacteriaceae. Clin Infect Dis. 2013 Sep. 57(6):781-8. [QxMD MEDLINE Link].

39. Harris PN, Wei JY, Shen AW, Abdile AA, Paynter S, Huxley RR, et al. Carbapenems versus alternative antibiotics for the treatment of bloodstream infections caused by Enterobacter, Citrobacter or Serratia species: a systematic review with meta-analysis. J Antimicrob Chemother. 2016 Feb. 71 (2):296-306. [QxMD MEDLINE Link].

40. Curtis L. Handwashing and other environmental controls needed to prevent hospital-acquired serratia infections. J Chemother. 2009 Aug. 21(4):470. [QxMD MEDLINE Link].

41. de Vries JJ, Baas WH, van der Ploeg K, et al. Outbreak of Serratia marcescens colonization and infection traced to a healthcare worker with long-term carriage on the hands. Infect Control Hosp Epidemiol. 2006 Nov. 27(11):1153-8. [QxMD MEDLINE Link].

Payal K Patel, MD, MPH Assistant Professor, Division of Infectious Diseases, Department of Internal Medicine, University of Michigan Health System; Medical Director of Antimicrobial Stewardship Program, Infectious Diseases Division, VA Ann Arbor Healthcare System

Payal K Patel, MD, MPH is a member of the following medical societies: American College of Physicians, HIV Medicine Association, Infectious Diseases Society of America, Society for Healthcare Epidemiology of America, Society of Hospital Medicine, Washtenaw County Medical Society

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

John L Brusch, MD, FACP Corresponding Faculty Member, Harvard Medical School

John L Brusch, MD, FACP is a member of the following medical societies: American College of Physicians, Infectious Diseases Society of America

Disclosure: Nothing to disclose.

Michael Stuart Bronze, MD David Ross Boyd Professor and Chairman, Department of Medicine, Stewart G Wolf Endowed Chair in Internal Medicine, Department of Medicine, University of Oklahoma Health Science Center; Master of the American College of Physicians; Fellow, Infectious Diseases Society of America; Fellow of the Royal College of Physicians, London

Michael Stuart Bronze, MD is a member of the following medical societies: Alpha Omega Alpha, American College of Physicians, American Medical Association, Association of Professors of Medicine, Infectious Diseases Society of America, Oklahoma State Medical Association, Southern Society for Clinical Investigation

Disclosure: Nothing to disclose.

Thomas E Herchline, MD Professor of Medicine, Wright State University, Boonshoft School of Medicine; Medical Consultant, Public Health, Dayton and Montgomery County (Ohio) Tuberculosis Clinic

Thomas E Herchline, MD is a member of the following medical societies: Alpha Omega Alpha, Infectious Diseases Society of America, Infectious Diseases Society of Ohio

Disclosure: Received research grant from: Regeneron.

Basilio J Anía, MD Associate Professor of Infectious Diseases, Universidad de Las Palmas de Gran Canaria; Consultant in Internal Medicine, Hospital Universitario Dr. Negrín, Spain

Disclosure: Nothing to disclose.

Antonette B Climaco, MD Attending Physician, Division of Infectious Diseases, Department of Medicine, Einstein Healthcare Network

Antonette B Climaco, MD is a member of the following medical societies: American Academy of HIV Medicine, HIV Medicine Association, Infectious Diseases Society of America, Philippine Medical Association

Disclosure: Nothing to disclose.

Prithiv J Prasad, MBBS Resident Physician, Department of Internal Medicine, Albert Einstein Medical Center

Disclosure: Nothing to disclose.

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