Chronic Fatigue Syndrome (CFS) Treatment & Management

Updated: May 19, 2017
  • Author: Burke A Cunha, MD; Chief Editor: Michael Stuart Bronze, MD  more...
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Approach Considerations

Because most cases of chronic fatigue syndrome (CFS) may be due to a viral infection, no uniformly effective therapy exists for CFS. Trials of antiviral agents have been ineffective in relieving the symptoms of CFS. In patients with elevated C pneumoniae levels, particularly those with increased immunoglobulin M (IgM) titers, antichlamydial therapy may be effective. No special diet or vitamin supplements are effective.

Otherwise, treatment is largely supportive and responsive to symptoms.



Exercise Therapy

In a 2017 Cochrane review, exercise therapy for patients with CFS was evaluated. The study found that patients felt less fatigued following exercise therapy and felt improved in respect to sleep, physical function, and general health. However, the authors could not conclude that exercise therapy improved the outcomes of pain, quality of life, anxiety, and/or depression. [12]