Stenotrophomonas Maltophilia Treatment & Management

Updated: Sep 16, 2021
  • Author: Sara Ahmed, MBBS, FCPS, MRCP(UK); Chief Editor: Michael Stuart Bronze, MD  more...
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Medical Care

Colonization of body fluids in hospitalized patients should be minimized if possible. Foley catheters should be used only as long as necessary and should be avoided if at all possible in immunocompromised hosts predisposed to urinary tract infections, eg, patients with diabetes, SLE, or multiple myeloma.

Colonization of respiratory secretions in intubated patients in ICUs is the rule and is difficult to prevent.

Patient-to-patient spread of organisms may be minimized or prevented by effective infection-control measures.



Consultation with an infectious disease specialist is essential for differentiating colonization from infection in patients with S maltophilia isolated from various body fluids.



Because S maltophilia is a common nosocomial colonizer in patients and medical fluids, the recovery of S maltophilia should be considered nonpathogenic unless proven otherwise.

If S maltophilia is recovered from several patients in the same area, sections of an ICU or ward can become the focus of further spread within the hospital setting.

Effective infection control measures can minimize or limit the spread of this and other organisms in the ICU.

Appropriate isolation procedures, rather than antimicrobial therapy, should be used to control the spread of S maltophilia.

Medical personnel, including medical students, housekeeping staff, attending physicians, nursing personnel, and respiratory therapists, are potential carriers of the organism from patient to patient.