Human Metapneumovirus Clinical Presentation

Updated: Jan 18, 2017
  • Author: Aliyah Baluch, MD, MSc, FACP; Chief Editor: Pranatharthi Haran Chandrasekar, MBBS, MD  more...
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Infection with human metapneumovirus (hMPV) causes a broad spectrum of respiratory illness, from mild symptoms to severe cough, bronchiolitis, and pneumonia. hMPV is believed to be transmitted via contaminated secretions such as saliva, droplets, or large-particle aerosols. The clinical symptoms are similar to those seen with RSV infection and may also include fever, myalgia, rhinorrhea, dyspnea, tachypnea, and wheezing. The average duration of fever during hMPV infection is 10 days. [51] Hospitalization, supplemental oxygen, and mechanical ventilation may be necessary in severe hMPV infections. [8, 9]

While bronchiolitis, with or without pneumonia, is the most common presentation of hMPV illness, other reported syndromes have included asthma exacerbation, otitis media, pneumonitis, flulike illness, community-acquired pneumonia, and COPD exacerbation. [1, 2, 3, 4, 5, 6, 7]