Bartter Syndrome Questions & Answers

Updated: May 30, 2019
  • Author: Lynda A Frassetto, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Questions & Answers

Overview

What is Bartter syndrome?

How is Bartter syndrome classified?

What is the pathophysiology of Bartter syndrome?

What is the pathophysiology of sensorineural deafness in Bartter syndrome?

What causes classic (type IVb) Bartter syndrome?

What causes Bartter syndrome?

What causes neonatal (type I and type II) Bartter syndrome?

What causes classic (type III) Bartter syndrome?

What causes classic (type IV) Bartter syndrome?

What causes classic (type V) Bartter syndrome?

What is the prevalence of Bartter syndrome in the US?

How does the prevalence of Bartter syndrome vary by geography?

At what age is Bartter syndrome typically diagnosed?

What is the prognosis of Bartter syndrome?

What is the mortality and morbidity associated with Bartter syndrome?

What is included in patient education about Bartter syndrome?

Presentation

Which clinical history findings are characteristic of neonatal Bartter syndrome?

Which clinical history findings are characteristic of classic Bartter syndrome?

Which physical findings are characteristic of neonatal Bartter syndrome?

Which physical findings are characteristic of classic Bartter syndrome?

DDX

How is Bartter syndrome differentiated from Gitelman syndrome?

Which conditions are included in the differential diagnoses of Bartter syndrome?

Workup

Which factors affect when symptoms develop in Bartter syndrome?

What is the role of electrocardiography in the workup of Bartter syndrome?

Which histologic findings are characteristic of Bartter syndrome?

When is inpatient care indicated for the treatment of Bartter syndrome?

Which specialist consultations are beneficial to patients with Bartter syndrome?

What is included in long-term monitoring of Bartter syndrome?

What is the role of potassium measurement in the workup of Bartter syndrome?

What is the role of aldosterone measurement in the workup of Bartter syndrome?

What is the role of chloride measurement in the workup of Bartter syndrome?

What is the role of calcium and magnesium in the workup of Bartter syndrome?

What is the prevalence of hyperuricemia in Bartter syndrome?

What is the role of CBC count in the workup of Bartter syndrome?

What is the role of genetic testing in the workup of Bartter syndrome?

What is the role of thiazide testing in the workup of Bartter syndrome?

What is the role of prenatal testing the workup of Bartter syndrome?

What is the role of GFR in the workup of Bartter syndrome?

What is the role of imaging studies in the workup of Bartter syndrome?

Treatment

How is Bartter syndrome treated?

How does Bartter syndrome affect pregnancy outcomes?

What is the role of renal transplantation in the treatment of Bartter syndrome?

What are considerations for donor selection in renal transplantation for Bartter syndrome?

What is the role of preemptive nephrectomy in the treatment of Bartter syndrome?

What concerns should be addressed in patients with Bartter syndrome undergoing surgical procedures?

What are potentials complications of anesthesia in patients with Bartter syndrome?

Which dietary modifications are used in the treatment of Bartter syndrome?

Which activity modifications are used in the treatment of Bartter syndrome?

Medications

What is the role of medications in the treatment of Bartter syndrome?

Which medications in the drug class NSAIDs are used in the treatment of Bartter Syndrome?

Which medications in the drug class ACE Inhibitors are used in the treatment of Bartter Syndrome?

Which medications in the drug class Diuretics, Potassium-Sparing are used in the treatment of Bartter Syndrome?

Which medications in the drug class Potassium Supplements are used in the treatment of Bartter Syndrome?