Uremic Encephalopathy Clinical Presentation

Updated: May 02, 2017
  • Author: James W Lohr, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Presentation

History

Early symptoms of uremic encephalopathy include the following:

  • Anorexia

  • Nausea

  • Restlessness

  • Drowsiness

  • Diminished ability to concentrate

  • Slowed cognitive functions

More severe signs and symptoms of uremic encephalopathy include the following:

  • Vomiting

  • Emotional volatility

  • Decreased cognitive function

  • Disorientation

  • Confusion

  • Bizarre behavior

  • Stupor, coma

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Physical

Physical examination findings may include the following:

  • Altered mental status (confusion)
  • Cranial nerve signs (nystagmus)
  • Papilledema
  • Hyperreflexia, clonus, asterixis
  • Altered gait
  • Stupor
  • Coma (occurs only if uremia remains untreated and progresses)
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