Hypercalcemia Questions & Answers

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7. Nissen PH, Christensen SE, Wallace A, et al. Multiplex ligation-dependent probe amplification (MLPA) screening for exon copy number variation in the calcium sensing receptor gene: no large rearrangements identified in patients with calcium metabolic disorders. Clin Endocrinol (Oxf). 2009 Nov 11. [QxMD MEDLINE Link].

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17. Cafforio P, Savonarola A, Stucci S, De Matteo M, Tucci M, Brunetti AE, et al. PTHrP produced by myeloma plasma cells regulates their survival and pro-osteoclast activity for bone disease progression. J Bone Miner Res. 2014 Jan. 29(1):55-66. [QxMD MEDLINE Link].

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19. Vallet N, Ertault M, Delaye JB, Chalopin T, Villate A, Drieu La Rochelle L, et al. Hypercalcemia is associated with a poor prognosis in lymphoma a retrospective monocentric matched-control study and extensive review of published reported cases. Ann Hematol. 2020 Feb. 99 (2):229-239. [QxMD MEDLINE Link].

20. Alsirafy SA, Sroor MY, Al-Shahri MZ. Hypercalcemia in advanced head and neck squamous cell carcinoma: prevalence and potential impact on palliative care. J Support Oncol. 2009 Sep-Oct. 7(5):154-7. [QxMD MEDLINE Link].

21. Durant E, Singh A. ST elevation due to hypercalcemia. Am J Emerg Med. 2017 Jul. 35 (7):1033.e3-1033.e6. [QxMD MEDLINE Link].

22. Sonoda K, Watanabe H, Hisamatsu T, Ashihara T, Ohno S, Hayashi H, et al. High Frequency of Early Repolarization and Brugada-Type Electrocardiograms in Hypercalcemia. Ann Noninvasive Electrocardiol. 2016 Jan. 21 (1):30-40. [QxMD MEDLINE Link].

23. Schutt RC, Bibawy J, Elnemr M, Lehnert AL, Putney D, Thomas AS, et al. Case report: Severe hypercalcemia mimicking ST-segment elevation myocardial infarction. Methodist Debakey Cardiovasc J. 2014 Jul-Sep. 10 (3):193-7. [QxMD MEDLINE Link]. [Full Text].

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25. Turner JJO. Hypercalcaemia - presentation and management. Clin Med (Lond). 2017 Jun. 17 (3):270-273. [QxMD MEDLINE Link].

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27. Hu MI, Glezerman IG, Leboulleux S, Insogna K, Gucalp R, Misiorowski W, et al. Denosumab for treatment of hypercalcemia of malignancy. J Clin Endocrinol Metab. 2014 Sep. 99(9):3144-52. [QxMD MEDLINE Link]. [Full Text].

28. Bergenfelz AO, Jansson SK, Wallin GK, et al. Impact of modern techniques on short-term outcome after surgery for primary hyperparathyroidism: a multicenter study comprising 2,708 patients. Langenbecks Arch Surg. 2009 Jul 18. [QxMD MEDLINE Link].

29. Low TH, Clark J, Gao K, et al. Outcome of parathyroidectomy for patients with renal disease and hyperparathyroidism: predictors for recurrent hyperparathyroidism. ANZ J Surg. 2009 May. 79(5):378-82. [QxMD MEDLINE Link].

30. [Guideline] Dickens LT, Derman B, Alexander JT. Endocrine Society Hypercalcemia of Malignancy Guidelines. JAMA Oncol. 2023 Jan 13. [QxMD MEDLINE Link]. [Full Text].

Mahendra Agraharkar, MD, MBBS, FACP, FASN Clinical Associate Professor of Medicine, Baylor College of Medicine; President and CEO, Space City Associates of Nephrology

Mahendra Agraharkar, MD, MBBS, FACP, FASN is a member of the following medical societies: American College of Physicians, American Society of Nephrology, National Kidney Foundation

Disclosure: Nothing to disclose.

O David Dellinger, III, MD Assistant Professor, Departments of Family Medicine and Internal Medicine, University of Alabama School of Medicine at Birmingham

O David Dellinger, III, MD is a member of the following medical societies: American Academy of Hospice and Palliative Medicine, American College of Physicians-American Society of Internal Medicine, American Geriatrics Society, AMDA - The Society for Post-Acute and Long-Term Care Medicine, American Society of Addiction Medicine

Disclosure: Nothing to disclose.

Arun Kumar Gangakhedkar, MD, FRACP Consultant in General Pediatrics, Starship Children's Hospital/Waitakere Hospital, New Zealand

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Christie P Thomas, MBBS, FRCP, FASN, FAHA Professor, Department of Internal Medicine, Division of Nephrology, Departments of Pediatrics and Obstetrics and Gynecology, Medical Director, Kidney and Kidney/Pancreas Transplant Program, University of Iowa Hospitals and Clinics

Christie P Thomas, MBBS, FRCP, FASN, FAHA is a member of the following medical societies: American College of Physicians, American Heart Association, American Society of Nephrology, Royal College of Physicians

Disclosure: Nothing to disclose.

Vecihi Batuman, MD, FASN Professor of Medicine, Section of Nephrology-Hypertension, Deming Department of Medicine, Tulane University School of Medicine

Vecihi Batuman, MD, FASN is a member of the following medical societies: American College of Physicians, American Society of Hypertension, American Society of Nephrology, Southern Society for Clinical Investigation

Disclosure: Nothing to disclose.

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