Hyperphosphatemia Differential Diagnoses

Updated: Dec 02, 2020
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Diagnostic Considerations

Pseudohyperphosphatemia is most commonly due to paraproteinemia from the following:

  • Waldenström macroglobulinemia

  • Multiple myeloma

  • Monoclonal gammopathy of unknown significance

Other differentials to be considered include the following:

  • Vitamin D intoxication

  • Oral saline laxative (Phospho-soda) abuse

  • Pseudohyperphosphatemia

  • Pseudohypoparathyroidism

  • Rhabdomyolysis

Differential Diagnoses