Lithium Nephropathy Questions & Answers

Updated: Jun 05, 2020
  • Author: Eleanor Lederer, MD, FASN; Chief Editor: Vecihi Batuman, MD, FASN  more...
  • Print
Questions & Answers

Overview

What is lithium nephropathy?

What is the historical evolution of lithium usage?

What is the pathophysiology of lithium nephropathy?

What causes central diabetes insipidus in lithium nephropathy?

What are causes nephrogenic diabetes insipidus in lithium nephropathy?

What is the prevalence of lithium nephropathy in the US?

What is the morbidity associated with lithium nephropathy?

Which patient groups are at highest risk for lithium nephropathy?

Presentation

Which clinical history findings are characteristic of lithium nephropathy?

Which physical findings are characteristic of lithium nephropathy?

DDX

What are the differential diagnoses for Lithium Nephropathy?

Workup

What is the role of lab testing in the diagnosis of lithium nephropathy?

What is the role of imaging studies in the diagnosis of lithium nephropathy?

Which tests can be performed in the evaluation of lithium nephropathy?

What is the role of water deprivation test in the diagnosis of lithium nephropathy?

What is the role of vasopressin challenge test in the diagnosis of lithium nephropathy?

Which histologic findings are characteristic of lithium nephropathy?

Treatment

How is lithium nephropathy treated?

Which specialist consultations are beneficial to patients with lithium nephropathy?

Medications

Which medications are used in the treatment of lithium nephropathy?

Which medications in the drug class Nonsteroidal Anti-inflammatory Drugs are used in the treatment of Lithium Nephropathy?

Which medications in the drug class Diuretics are used in the treatment of Lithium Nephropathy?

Follow-up

What long-term monitoring is needed following treatment of lithium nephropathy?

What is included in inpatient care for lithium nephropathy?

How is lithium intoxication prevented?

What are the possible complications of lithium nephropathy?

What is the prognosis of lithium nephropathy?