Metabolic Alkalosis Questions & Answers

Updated: Dec 10, 2020
  • Author: Christie P Thomas, MBBS, FRCP, FASN, FAHA; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Questions & Answers

Overview

What is metabolic alkalosis?

What is the pathogenesis of metabolic alkalosis?

What are the pathogenic mechanisms of metabolic alkalosis?

What is the pathophysiology of metabolic alkalosis maintenance?

What are the most common causes of metabolic alkalosis?

What causes chloride-responsive metabolic alkalosis?

What causes chloride-resistant metabolic alkalosis?

What are the non-chloride-related causes of metabolic alkalosis?

What causes metabolic alkalosis?

What is the prevalence of metabolic alkalosis?

What are the mortality rates of metabolic alkalosis?

Presentation

What are the signs and symptoms of metabolic alkalosis?

What is the focus of the clinical history to evaluate for metabolic alkalosis?

Which physical findings are characteristic of metabolic alkalosis?

Which physical findings are characteristic of bulimia in metabolic alkalosis?

Which physical findings are characteristic of Cushing syndrome in metabolic alkalosis?

Which physical findings are characteristic of congenital adrenal hyperplasia (CAH) in metabolic alkalosis?

What are the possible complications of metabolic alkalosis?

DDX

How is respiratory acidosis differentiated from metabolic alkalosis?

What are the differential diagnoses for Metabolic Alkalosis?

Workup

How is metabolic alkalosis diagnosed?

What is the role of serum anion gap in the workup of metabolic alkalosis?

What is the role of urine sodium ion concentration in the workup of metabolic alkalosis?

What is the role of plasma renin activity in the workup of metabolic alkalosis?

How is primary hyperaldosteronism diagnosed in the workup of metabolic alkalosis?

How is Cushing syndrome diagnosed in the workup of metabolic alkalosis?

How is syndrome of apparent mineralocorticoid excess (AME) diagnosed in the workup of metabolic alkalosis?

How are congenital adrenal hyperplasia variants differentiated in the workup of metabolic alkalosis?

What is the role of a diuretic screen in the workup of metabolic alkalosis?

What is the role of imaging in the workup of metabolic alkalosis?

What is the role of genetic analysis in the work up of metabolic alkalosis?

Treatment

How is metabolic alkalosis treated?

How is chloride-responsive metabolic alkalosis treated?

How is chloride-resistant metabolic alkalosis treated?

How is metabolic alkalosis treated in primary hyperaldosteronism?

How is metabolic alkalosis treated in Cushing syndrome?

How is metabolic alkalosis treated in syndrome of apparent mineralocorticoid excess (AME)?

How is metabolic alkalosis treated following licorice ingestion?

How is metabolic alkalosis treated in Bartter and Gitelman syndromes?

How is metabolic alkalosis treated in Liddle syndrome?

What is the role of hydrochloric acid in the treatment of metabolic alkalosis?

What is the role of dialysis in the treatment of metabolic alkalosis?

Which specialist consultations are beneficial to patients with metabolic alkalosis?

Medications

Which medications are used in the treatment of metabolic alkalosis?

Which medications in the drug class Nonsteroidal Anti-inflammatory Agents are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Corticosteroids are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Fluid Replacements are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Potassium Supplements are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Angiotensin-Converting Enzyme Inhibitors are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Potassium-Sparing Diuretics are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Acids are used in the treatment of Metabolic Alkalosis?

Which medications in the drug class Carbonic Anhydrase Inhibitors are used in the treatment of Metabolic Alkalosis?