Minimal-Change Disease Questions & Answers

Updated: Dec 24, 2018
  • Author: Abeera Mansur, MD; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Questions & Answers

Overview

What is minimal-change disease (MCD)?

What is the pathophysiology of minimal-change disease (MCD)?

What is the prevalence of minimal-change disease (MCD) in the US?

What is the mortality and morbidity associated with minimal-change disease (MCD)?

Which patient groups have the highest prevalence of minimal-change disease (MCD)?

Presentation

Which clinical history findings are characteristic of minimal-change disease (MCD)?

What are the signs and symptoms of minimal-change disease (MCD)?

What causes minimal-change disease (MCD)?

Which physical findings are characteristic of minimal-change disease (MCD)?

DDX

Which conditions are included in the differential diagnoses of minimal-change disease (MCD)?

Workup

How is minimal-change disease (MCD) diagnosed?

What is the role of biomarkers in the diagnosis of minimal-change disease (MCD)?

Which light microscopy findings are characteristic of minimal-change disease (MCD)?

Which immunohistologic findings are characteristic of minimal-change disease (MCD)?

Which electron microscopy findings are characteristic of minimal-change disease (MCD)?

Treatment

How is minimal-change disease (MCD) treated?

Which specialist consultations are beneficial to patients with minimal-change disease (MCD)?

Which dietary and activity modifications are used in the treatment of minimal-change disease (MCD)?

Medications

What is the role of medications in the treatment of minimal-change disease (MCD)?

How is the response to steroids determined in the treatment of minimal-change disease (MCD)?

Which medications are used in the treatment of minimal-change disease (MCD)?

Which medications in the drug class Immunomodulators are used in the treatment of Minimal-Change Disease?

Which medications in the drug class Immunosuppressant agents are used in the treatment of Minimal-Change Disease?

Which medications in the drug class Antineoplastic agents are used in the treatment of Minimal-Change Disease?

Which medications in the drug class Corticosteroids are used in the treatment of Minimal-Change Disease?

Which medications in the drug class Diuretics are used in the treatment of Minimal-Change Disease?

Follow-up

What is included in the long-term monitoring of minimal-change disease (MCD)?

What are the possible complications of minimal-change disease (MCD) treatment?

What is the prognosis of minimal-change disease (MCD)?

What is included in the patient education about minimal-change disease (MCD)?