Nephrocalcinosis Differential Diagnoses

Updated: Dec 07, 2015
  • Author: Tibor Fulop, MD, FASN, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Diagnostic Considerations

Nephrocalcinosis, though seemingly a simple finding, incorporates numerous potential disease processes in the differential. An effort should be made to describe the location and degree of nephrocalcinosis and to uncover the underlying metabolic abnormality or abnormalities (eg, renal tubular acidosis). In clinical practice, nephrocalcinosis is more commonly encountered in its macroscopic form than in its microscopic form. It must not be considered synonymous with renal stone disease, because it has much broader metabolic implications.