Hypersensitivity Nephropathy Follow-up

Updated: Dec 01, 2015
  • Author: Micah L Thorp, DO, MPH; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Follow-up

Further Outpatient Care

See the list below:

  • Most cases of acute interstitial nephritis (AIN) are diagnosed in the hospital setting. Carefully monitor renal function until resolved.

  • Make patients aware of any drug that may have caused the episode of acute interstitial nephritis, and advise them not to take it again.

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Prognosis

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  • If acute interstitial nephritis is detected early and the offending agent is removed, the patient will most likely return to baseline renal function. If the diagnosis is overlooked or if the patient is rechallenged with the same offending agent, the initial inflammatory response may become chronic, leading to fibrosis and tubular atrophy.

  • The prognosis is further delineated by the pathology found at biopsy. Patients with a diffuse infiltrate have a poorer prognosis than those without. In addition, the presence of 1-6% neutrophils in the infiltrate suggests a poorer prognosis.

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Patient Education

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  • Educate patients about agents that lead to acute interstitial nephritis, and instruct them to avoid using the offending agents.

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