Medication
Medication Summary
The goals of pharmacotherapy are to reduce morbidity and to prevent complications. Management focuses on discontinuation of the offending agents or treatment of the underlying infection, but if kidney function does not subsequently improve, corticosteroid therapy may be considered.
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Corticosteroids
Class Summary
Have anti-inflammatory properties and cause profound and varied metabolic effects. Corticosteroids modify the body's immune response to diverse stimuli.
Prednisone (Deltasone, Orasone, Sterapred)
Prednisone is the drug of choice for acute interstitial nephritis that has not responded to removal of the offending agents.
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Media Gallery
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Acute interstitial nephritis with mononuclear cell infiltrate.
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Mononuclear cell infiltrate between tubules.
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