Familial Renal Amyloidosis Questions & Answers

Updated: Nov 21, 2018
  • Author: Helen J Lachmann, MD, MRCP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Questions & Answers

Overview

What is familial renal amyloidosis (FRA)?

What is the pathophysiology of familial renal amyloidosis (FRA)?

What is the prevalence of familial renal amyloidosis (FRA)?

What is the mortality and morbidity associated with familial renal amyloidosis (FRA)?

What are the racial predilections of familial renal amyloidosis (FRA)?

What are the sexual predilections of familial renal amyloidosis (FRA)?

At what age does familial renal amyloidosis (FRA) typically first present?

Presentation

Which clinical history findings are characteristic of familial renal amyloidosis (FRA)?

Which physical findings are characteristic of familial renal amyloidosis (FRA)?

What is the role of fibrinogen in the etiology of familial renal amyloidosis (FRA)?

What causes familial renal amyloidosis (FRA)?

What is the role of lysozyme in the etiology of familial renal amyloidosis (FRA)?

What is the role of apolipoprotein AI in the etiology of familial renal amyloidosis (FRA)?

What is the role of apolipoprotein AII in the etiology of familial renal amyloidosis (FRA)?

DDX

What are the differential diagnoses for Familial Renal Amyloidosis?

Workup

What is the role of lab tests in the workup of familial renal amyloidosis (FRA)?

What is the role of protein-to-creatinine (Pr/Cr) ratio in the workup of familial renal amyloidosis (FRA)?

What is the role of liver function tests in the workup of familial renal amyloidosis (FRA)?

What is the role of hematological indices and coagulation tests in the workup of familial renal amyloidosis (FRA)?

What is the role of imaging in the workup of familial renal amyloidosis (FRA)?

What is the role of scintigraphy in the workup of familial renal amyloidosis (FRA)?

What is the role of echocardiography in the workup of familial renal amyloidosis (FRA)?

What is the role of DNA analysis in the workup of familial renal amyloidosis (FRA)?

What is the role of fibril protein sequencing in the workup of familial renal amyloidosis (FRA)?

What is the role of biopsy in the workup of familial renal amyloidosis (FRA)?

Which histologic findings are characteristic of familial renal amyloidosis (FRA)?

Treatment

How is familial renal amyloidosis (FRA) treated?

What is the role of surgery in the treatment of familial renal amyloidosis (FRA)?

What is the role of kidney transplantation in the treatment of familial renal amyloidosis (FRA)?

What is the role of liver transplantation in the treatment of familial renal amyloidosis (FRA)?

What is the role of heart transplantation in the treatment of familial renal amyloidosis (FRA)?

Which specialist consultations are beneficial to patients with familial renal amyloidosis (FRA)?

Medications

What is the role of medications in the treatment of familial renal amyloidosis (FRA)?

Which medications in the drug class Prokinetic agents are used in the treatment of Familial Renal Amyloidosis?

Which medications in the drug class Histamine2-receptor antagonists are used in the treatment of Familial Renal Amyloidosis?

Which medications in the drug class Proton pump inhibitors are used in the treatment of Familial Renal Amyloidosis?

Which medications in the drug class Diuretics are used in the treatment of Familial Renal Amyloidosis?

Which medications in the drug class Antihypertensive agents are used in the treatment of Familial Renal Amyloidosis?

Follow-up

What is included in the long-term monitoring of familial renal amyloidosis?

What is the role of genetic screening in familial renal amyloidosis?

What are the possible complications of familial renal amyloidosis?

What is the prognosis of familial renal amyloidosis?

What is included in patient education about familial renal amyloidosis?