Dialysis-Related Beta-2m Amyloidosis Questions & Answers

Updated: Nov 14, 2019
  • Author: Anita Basu, MD, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Questions & Answers

Overview

What is beta-2-microglobulin (beta-2m) amyloidosis?

What causes beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of dialysis in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of the dialysis membrane in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of diuresis and uremia in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of cytokines in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of advanced glycation end products (AGEs) in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of dialysate in the etiology of beta-2-microglobulin (beta-2m) amyloidosis?

What is the prevalence of beta-2-microglobulin (beta-2m) amyloidosis?

What is the prognosis of beta-2-microglobulin (beta-2m) amyloidosis?

What is the morbidity and mortality associated with beta-2-microglobulin (beta-2m) amyloidosis?

Presentation

Which clinical history findings are characteristic of beta-2-microglobulin (beta-2m) amyloidosis?

Which osteoarticular conditions are associated with beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of carpal tunnel syndrome in beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of flexor tenosynovitis in beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of scapulohumeral arthropathy in beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of spondyloarthropathy in beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of bone cysts in beta-2-microglobulin (beta-2m) amyloidosis?

Which are the signs and symptoms of systemic involvement of beta-2-microglobulin (beta-2m) amyloidosis?

Which GI conditions are associated with beta-2-microglobulin (beta-2m) amyloidosis?

What are the signs and symptoms of cardiac involvement in beta-2-microglobulin (beta-2m) amyloidosis?

Which genitourinary tract conditions are associated with beta-2-microglobulin (beta-2m) amyloidosis?

Which physical findings are characteristic of beta-2-microglobulin (beta-2m) amyloidosis?

What is the clinical staging of beta-2-microglobulin (beta-2m) amyloidosis?

DDX

How is Dupuytren contracture differentiated from beta-2-microglobulin (beta-2m) amyloidosis?

How is secondary hyperparathyroidism differentiated from beta-2-microglobulin (beta-2m) amyloidosis?

How is renal osteodystrophy differentiated from beta-2-microglobulin (beta-2m) amyloidosis?

How is aluminum overload differentiated from beta-2-microglobulin (beta-2m) amyloidosis?

Which types of amyloidosis should be included in the differential diagnoses of beta-2-microglobulin (beta-2m) amyloidosis?

Workup

How is dialysis-related beta-2-microglobulin (beta-2m) amyloidosis diagnosed?

What is the role of radiography in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of CT scanning in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of MRI in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of ultrasonography in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of scintigraphy in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of biopsy in the workup of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

Treatment

How is dialysis-related beta-2-microglobulin (beta-2m) amyloidosis treated?

Which surgical procedures may be beneficial in the treatment of dialysis-related beta-2-microglobulin (beta-2m) amyloidosis?

What is the role of an apheresis device in beta-2-microglobulin (beta-2m) amyloidosis treatment?

Which specialist consultations may be beneficial to patients with beta-2-microglobulin (beta-2m) amyloidosis?

How is beta-2-microglobulin (beta-2m) amyloidosis prevented?

What is the role of online hemodiafiltration in beta-2-microglobulin (beta-2m) amyloidosis prevention?

What is the role of high-flux dialyzers in beta-2-microglobulin (beta-2m) amyloidosis prevention?

What is the role of ultrapure dialysate preparations in beta-2-microglobulin (beta-2m) amyloidosis prevention?

What is the role of direct hemoperfusion-type adsorption column (Lixelle) in beta-2-microglobulin (beta-2m) amyloidosis prevention?

What is the role of laser therapy in beta-2-microglobulin (beta-2m) amyloidosis prevention?

What is the role of kidney transplantation in beta-2-microglobulin (beta-2m) amyloidosis treatment?

Medications

Which medications are used in beta-2-microglobulin (beta-2m) amyloidosis treatment?

Which medications in the drug class Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) are used in the treatment of Dialysis-Related Beta-2m Amyloidosis?

Which medications in the drug class Analgesics, Topical are used in the treatment of Dialysis-Related Beta-2m Amyloidosis?

Which medications in the drug class Immunosuppressants are used in the treatment of Dialysis-Related Beta-2m Amyloidosis?