Acquired Cystic Kidney Disease Follow-up

Updated: Mar 13, 2020
  • Author: Manish Suneja, MD, FASN, FACP; Chief Editor: Vecihi Batuman, MD, FASN  more...
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Further Outpatient Care

See the list below:

  • If the cyst is less than 3 cm in diameter and no bleeding has occurred, follow up with imaging studies.

  • If tumor enlargement is present with associated persistent hematuria, consider surgery if the patient's status permits.



Acquired cystic kidney disease reverses in some patients after successful renal transplantation. Some native kidneys continue to develop cysts after transplantation, and in these patients, renal function conceivably remains significantly compromised, thereby maintaining the cystogenic state. Cyclosporine use has been associated with a greater prevalence of post-transplant ACKD than in the  pre-cyclosoporine era. [28]

Cysts do not develop in other organs, in contrast to autosomal dominant polycystic kidney disease (ADPKD).

Acquired cystic kidney disease can be progressive if the patient is on dialysis for an extended period; malignant transformation may also occur. The 5-year survival rates after diagnosis of malignancy are comparable to those observed in renal cell carcinoma in the general population. Renal cell carcinoma in patients with ESRD is associated with more favorable histologic features and prognosis. [29]  Death is usually associated with metastasis and accounts for 2% of the deaths in renal transplant patients.