Hip Arthroscopy Medication

Updated: May 31, 2016
  • Author: Bart Eastwood, DO; Chief Editor: Dinesh Patel, MD, FACS  more...
  • Print
Medication

Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications. A standard-dose nonsteroidal anti-inflammatory drug (NSAID) or aspirin is used for prophylaxis of heterotopic ossification for at least 3 weeks after hip arthroscopy. 

Next:

NSAIDs

Class Summary

NSAIDs have analgesic, anti-inflammatory, and antipyretic activities. Their mechanism of action is not known, but they may inhibit cyclooxygenase (COX) activity and prostaglandin synthesis. Other mechanisms may exist as well, such as inhibition of leukotriene synthesis, lysosomal enzyme release, lipoxygenase activity, neutrophil aggregation, and various cell membrane functions.

Ibuprofen (Advil, Motrin, Caldolor)

Ibuprofen is the drug of choice for patients with mild-to-moderate pain. It inhibits inflammatory reactions and pain by decreasing prostaglandin synthesis.

Naproxen (Aleve, Anaprox, Anaprox DS, Flanax Pain Relief, Mediproxen)

Naproxen is used for the relief of mild-to-moderate pain. It inhibits inflammatory reactions and pain by decreasing COX activity, which results in decreased prostaglandin synthesis.

Ketoprofen (Active-Ketoprofen)

Ketoprofen is used for relief of mild-to-moderate pain and inflammation. Small dosages are indicated initially in small patients, elderly patients, and patients with renal or liver disease. Doses higher than 75 mg do not increase the therapeutic effects. Administer high doses with caution, and closely observe the patient’s response.

Aspirin (Bayer Aspirin Extra Strength, Aspercin, Ascriptin Regular Strength, Bufferin, Durlaza)

Aspirin blocks prostaglandin synthetase action, which in turn inhibits prostaglandin synthesis and prevents the formation of platelet-aggregating thromboxane A2; it acts on the hypothalamic heat-regulating center to reduce fever.

Indomethacin (Indocin, Tivorbex)

Indomethacin is thought to be the most effective NSAID for the treatment of AS, though no scientific evidence supports this claim. It is used for relief of mild-to-moderate pain; it inhibits inflammatory reactions and pain by decreasing the activity of COX, which results in a decrease of prostaglandin synthesis.

Previous