Obesity and Pregnancy Medication

Updated: Oct 18, 2021
  • Author: Dawn M Palaszewski, MD; Chief Editor: Edward H Springel, MD, FACOG  more...
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Medication Summary

The goals of pharmacotherapy are to reduce morbidity and prevent complications.



Class Summary

Therapy must cover all likely pathogens in the context of this clinical setting. Prophylactic antibiotics should be administered based on maternal weight.


First-generation semisynthetic cephalosporin that arrests bacterial cell wall synthesis, inhibiting bacterial growth. Based on general surgical procedures, the suggested recommended dose is a 2-g prophylactic dose for women who weigh >80 kg (175 lb), with an increase to 3 g for those who weight >120 kg (265 lb). Another suggested option is to repeat the dose in 4 hours.