Abruptio Placentae Questions & Answers

1. Abu-Heija A, al-Chalabi H, el-Iloubani N. Abruptio placentae: risk factors and perinatal outcome. J Obstet Gynaecol Res. 1998 Apr. 24(2):141-4. [QxMD MEDLINE Link].

2. Oyelese Y, Ananth CV. Placental abruption. Obstet Gynecol. 2006 Oct. 108(4):1005-16.

3. Workalemahu T, Enquobahrie DA, Gelaye B, Thornton TA, Tekola-Ayele F, Sanchez SE, et al. Abruptio placentae risk and genetic variations in mitochondrial biogenesis and oxidative phosphorylation: replication of a candidate gene association study. Am J Obstet Gynecol. 2018 Dec. 219 (6):617.e1-617.e17. [QxMD MEDLINE Link].

4. Ananth CV, Oyelese Y, Yeo L, Pradhan A, Vintzileos AM. Placental abruption in the United States, 1979 through 2001: temporal trends and potential determinants. Am J Obstet Gynecol. 2005 Jan. 192(1):191-8. [QxMD MEDLINE Link].

5. Rana A, Sawhney H, Gopalan S. Abruptio placentae and chorioamnionitis-microbiological and histologic correlation. Acta Obstet Gynecol Scand. 1999 May. 78(5):363-6. [QxMD MEDLINE Link].

6. Tuuli MG, Norman SM, Odibo AO, Macones GA, Cahill AG. Perinatal outcomes in women with subchorionic hematoma: a systematic review and meta-analysis. Obstet Gynecol. 2011 May. 117(5):1205-12. [QxMD MEDLINE Link].

7. Ananth CV, Smulian JC, Vintzileos AM. Incidence of placental abruption in relation to cigarette smoking and hypertensive disorders during pregnancy: a meta-analysis of observational studies. Obstet Gynecol. 1999 Apr. 93(4):622-8. [QxMD MEDLINE Link].

8. Ananth CV, Savitz DA, Luther ER. Maternal cigarette smoking as a risk factor for placental abruption, placenta previa, and uterine bleeding in pregnancy. Am J Epidemiol. 1996 Nov 1. 144(9):881-9. [QxMD MEDLINE Link].

9. Ananth CV, Savitz DA, Bowes WA Jr, Luther ER. Influence of hypertensive disorders and cigarette smoking on placental abruption and uterine bleeding during pregnancy. Br J Obstet Gynaecol. 1997 May. 104(5):572-8. [QxMD MEDLINE Link].

10. Hoskins IA, Friedman DM, Frieden FJ. Relationship between antepartum cocaine abuse, abnormal umbilical artery Doppler velocimetry, and placental abruption. Obstet Gynecol. 1991 Aug. 78(2):279-82. [QxMD MEDLINE Link].

11. Tikkanen M, Nuutila M, Hiilesmaa V, Paavonen J, Ylikorkala O. Clinical presentation and risk factors of placental abruption. Acta Obstet Gynecol Scand. 2006. 85(6):700-5. [QxMD MEDLINE Link].

12. Ananth CV, Wilcox AJ. Placental abruption and perinatal mortality in the United States. Am J Epidemiol. 2001 Feb 15. 153(4):332-7. [QxMD MEDLINE Link].

13. Tikkanen M, Luukkaala T, Gissler M, et al. Decreasing perinatal mortality in placental abruption. Acta Obstet Gynecol Scand. 2013 Mar. 92(3):298-305. [QxMD MEDLINE Link].

14. Raymond EG, Mills JL. Placental abruption. Maternal risk factors and associated fetal conditions. Acta Obstet Gynecol Scand. 1993 Nov. 72(8):633-9. [QxMD MEDLINE Link].

15. Pariente G, Shoham-Vardi I, Kessous R, et al. Placental abruption as a significant risk factor for long-term cardiovascular mortality in a follow-up period of more than a decade. Paediatr Perinat Epidemiol. 2014 Jan. 28(1):32-8. [QxMD MEDLINE Link].

16. Clark SL. Placentae previa and abruptio placentae. Creasy RK, Resnik R, eds. Maternal Fetal Medicine. 5th ed. Philadelphia, Pa: WB Saunders; 2004. 715.

17. Glantz C, Purnell L. Clinical utility of sonography in the diagnosis and treatment of placental abruption. J Ultrasound Med. 2002 Aug. 21(8):837-40. [QxMD MEDLINE Link].

18. Kramer MS, Usher RH, Pollack R. Etiologic determinants of abruptio placentae. Obstet Gynecol. 1997 Feb. 89(2):221-6. [QxMD MEDLINE Link].

19. Ananth CV, Wapner RJ, Ananth S, DʼAlton ME, Vintzileos AM. First-Trimester and Second-Trimester Maternal Serum Biomarkers as Predictors of Placental Abruption. Obstet Gynecol. 2017 Mar. 129 (3):465-472. [QxMD MEDLINE Link].

20. ACOG Committee Opinion. Antenatal Corticosteroid Therapy for Fetal Maturation. ACOG. Available at https://www.acog.org/-/media/Committee-Opinions/Committee-on-Obstetric-Practice/co677.pdf?dmc=1&ts=20160922T2345049022. Number 677, October 2016; Accessed: November 23, 2016.

21. Meguerdichian D. Complications in late pregnancy. Emerg Med Clin North Am. 2012 Nov. 30(4):919-36. [QxMD MEDLINE Link].

22. Schmidt P, Raines DA. Placental Abruption (Abruptio Placentae). 2018 Jan. [QxMD MEDLINE Link]. [Full Text].

Shad H Deering, MD Medical Director, Andersen Simulation Center, Madigan Army Medical Center

Shad H Deering, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists, Association of Professors of Gynecology and Obstetrics, Society for Maternal-Fetal Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

John G Pierce, Jr, MD Chairman of Women’s Health and Medical Specialties, Liberty University College of Osteopathic Medicine; Obstetrician/Gynecologist, Women’s Health of Central Virginia

John G Pierce, Jr, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists, Association of Professors of Gynecology and Obstetrics, Christian Medical and Dental Associations, Medical Society of Virginia, Society of Laparoscopic and Robotic Surgeons

Disclosure: Nothing to disclose.

Carl V Smith, MD The Distinguished Chris J and Marie A Olson Chair of Obstetrics and Gynecology, Professor, Department of Obstetrics and Gynecology, Senior Associate Dean for Clinical Affairs, University of Nebraska Medical Center

Carl V Smith, MD is a member of the following medical societies: American College of Obstetricians and Gynecologists, American Institute of Ultrasound in Medicine, Association of Professors of Gynecology and Obstetrics, Central Association of Obstetricians and Gynecologists, Society for Maternal-Fetal Medicine, Council of University Chairs of Obstetrics and Gynecology, Nebraska Medical Association

Disclosure: Nothing to disclose.

Bruce A Meyer, MD, MBA Executive Vice President for Health System Affairs, Executive Director, Faculty Practice Plan, Professor, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical School

Bruce A Meyer, MD, MBA is a member of the following medical societies: Medical Group Management Association, American College of Obstetricians and Gynecologists, American Association for Physician Leadership, American Institute of Ultrasound in Medicine, Association of Professors of Gynecology and Obstetrics, Massachusetts Medical Society, Society for Maternal-Fetal Medicine

Disclosure: Nothing to disclose.

The authors and editors of Medscape Reference gratefully acknowledge the contributions of previous author Andrew Satin, MD, to the development and writing of the source article.

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