Granulosa-Theca Cell Tumors Questions & Answers

Updated: Aug 30, 2018
  • Author: David C Starks, MD, MPH; Chief Editor: Warner K Huh, MD  more...
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Questions & Answers

Overview

What are granulosa cell tumors (GCTs) of the ovaries?

What is the pathophysiology of granulosa cell tumors (GCTs) of the ovaries?

What is the US prevalence of granulosa cell tumors (GCTs) of the ovaries?

What is the global prevalence of granulosa cell tumors (GCTs) of the ovaries?

What is the morbidity and mortality associated with granulosa cell tumors (GCTs) of the ovaries?

What are the racial predilections of granulosa cell tumors (GCTs) of the ovaries?

What is the prevalence of granulosa cell tumors (GCTs) of the testes?

Which age groups have the highest prevalence of granulosa cell tumors (GCTs) of the ovaries?

Presentation

Which clinical history findings are characteristic of granulosa cell tumors (GCTs) of the ovaries?

What are the signs and symptoms of granulosa cell tumors (GCTs) of the ovaries in prepubertal girls?

What are the signs and symptoms of granulosa cell tumors (GCTs) of the ovaries in premenopausal women?

What are the signs and symptoms of granulosa cell tumors (GCTs) of the ovaries in postmenopausal women?

Which physical findings are characteristic of granulosa cell tumors (GCTs) of the ovaries?

What causes granulosa cell tumors (GCTs) of the ovaries?

DDX

How are granulosa cell tumors (GCTs) of the ovaries diagnosed?

How are granulosa cell tumors (GCTs) of the ovaries treated during pregnancy?

Which conditions are included in the differential diagnoses of

What are the differential diagnoses for Granulosa-Theca Cell Tumors?

Workup

What is the role of lab tests in the workup of granulosa cell tumors (GCTs) of the ovaries?

What is the role of inhibin measurement in the workup of granulosa cell tumors (GCTs) of the ovaries?

What is the role of AMH and MIS hormone testing in the workup of granulosa cell tumors (GCTs) of the ovaries

What is the role of GCT testing in the workup of granulosa cell tumors (GCTs) of the ovaries?

What is the role of ultrasonography in the workup of granulosa cell tumors (GCTs) of the ovaries?

What is the role of roentgenography in the workup of granulosa cell tumors (GCTs) of the ovaries?

What is the role of mammography in the workup of granulosa cell tumors (GCTs) of the ovaries?

Which histologic findings are characteristic of granulosa cell tumors (GCTs) of the ovaries?

How are granulosa cell tumors (GCTs) of the ovaries staged?

How are stage I granulosa cell tumors (GCTs) of the ovaries defined?

How are stage II granulosa cell tumors (GCTs) of the ovaries defined?

How are stage III granulosa cell tumors (GCTs) of the ovaries defined?

How are stage IV granulosa cell tumors (GCTs) of the ovaries defined?

Treatment

How are granulosa cell tumors (GCTs) of the ovaries treated?

What is the role of surgery in the treatment of granulosa cell tumors (GCTs) of the ovaries?

Which specialist consultations are beneficial to patients with granulosa cell tumors (GCTs) of the ovaries?

What are the benefits of consultation with a gastroenterologist for patients with granulosa cell tumors (GCTs) of the ovaries?

Which dietary modifications are used in the treatment of granulosa cell tumors (GCTs) of the ovaries?

Which activity modifications are used in the treatment of granulosa cell tumors (GCTs) of the ovaries?

Medications

What is the role of medications in the treatment of granulosa cell tumors (GCTs) of the ovaries?

What is the efficacy of the BEP regimen in the treatment of granulosa cell tumors (GCTs) of the ovaries?

What is the efficacy of the PVB regimen in the treatment of granulosa cell tumors (GCTs) of the ovaries?

Which older multidrug regimens have been used in the treatment of granulosa cell tumors (GCTs) of the ovaries?

How are advanced juvenile granulosa cell tumors (JGCTs) of the ovaries treated?

Which experimental medications are being investigated for the treatment of granulosa cell tumors (GCTs) of the ovaries?

Which medications in the drug class Antiemetics are used in the treatment of Granulosa-Theca Cell Tumors?

Which medications in the drug class Uroprotective agents are used in the treatment of Granulosa-Theca Cell Tumors?

Which medications in the drug class Antineoplastic agents are used in the treatment of Granulosa-Theca Cell Tumors?

Follow-up

What is included in the long-term monitoring of granulosa cell tumors (GCTs) of the ovaries?

What is the role of antiemetics in the treatment of granulosa cell tumors (GCTs) of the ovaries?

What is the role of hematopoietic growth factors in the treatment of granulosa cell tumors (GCTs) of the ovaries?

When is patient transfer required for the treatment of granulosa cell tumors (GCTs) of the ovaries?

How is granulosa cell tumors (GCTs) of the ovaries prevented?

What are the possible complications of granulosa cell tumors (GCTs)?

What is the prognosis of granulosa cell tumors (GCTs)?

What is included in patient education about granulosa cell tumors (GCTs)?