Hyperemesis Gravidarum Differential Diagnoses

Updated: Apr 12, 2022
  • Author: Dotun A Ogunyemi, MD; Chief Editor: Christine Isaacs, MD  more...
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Diagnostic Considerations

Important considerations

It is important to consider other diagnoses in cases of severe refractory nausea and vomiting during pregnancy, especially if the presentation is atypical or other symptoms are present.

It is vital to fully inform patients of the available evidence regarding potential risks and benefits of all treatments administered for hyperemesis gravidarum, especially regarding the effects of medications on the fetus. If not emergently required, avoid the administration of drugs during the first 10 weeks of gestation if possible.

Other problems to be considered

Other conditions to consider in the differential diagnosis of patients with suspected hyperemesis gravidarum include the following:

  • Drug toxicity

  • Eating disorders

  • Gastroparesis

  • Migraines

  • Ovarian torsion

  • Pseudotumor cerebri

  • Psychological disorders

  • Tumors of the central nervous system

  • Vestibular lesions

Differential Diagnoses