Luteal Phase Dysfunction Follow-up

Updated: Dec 09, 2016
  • Author: Thomas L Alderson, DO; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Follow-up

Further Outpatient Care

All diagnostic testing and treatment can be performed in an outpatient setting.

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Further Inpatient Care

Luteal phase dysfunction does not require hospitalization and therefore no inpatient diagnostic workup or treatment.

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Inpatient & Outpatient Medications

See the list below:

  • Medications used to treat luteal phase dysfunction include dopamine receptor agonists to treat elevated serum prolactin levels.
  • Thyroid replacement treats hypothyroidism.
  • Supplemental progesterone increases the lower levels in the luteal phase observed with this condition.
  • Clomiphene citrate enhances follicular development and thus increases luteal-phase progesterone levels.
  • Human menopausal gonadotropins enhance follicular development and increase luteal-phase progesterone levels.
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Deterrence/Prevention

No methodology prevents luteal phase defect. Maintain a high level of clinical suspicion that such a condition exists when seeing a patient with infertility or recurrent pregnancy loss.

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Complications

Complications are associated with the endometrial biopsy. Be cautious when performing the biopsy to avoid perforating the uterus. Advise patients to take a nonsteroidal anti-inflammatory drug (NSAID) prior to the procedure to alleviate uterine cramping. No antibiotic prophylaxis is needed.

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Prognosis

The lack of double-blinded placebo-controlled studies prevents an accurate prognosis for this condition. A report by the Practice Committee of the American Society for Reproductive Medicine concluded that there is no significant evidence that LPD alone can cause infertility. [7]

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Patient Education

Patients should keep an accurate menstrual cycle calendar. Abnormal cycle length may heighten the physician's suspicion that a luteal phase dysfunction exists.

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