Meigs Syndrome Clinical Presentation

Updated: Feb 19, 2021
  • Author: Klaus-Dieter Lessnau, MD, FCCP; Chief Editor: Leslie M Randall, MD, MAS, FACS  more...
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Patients with Meigs syndrome may have a family history of ovarian cancer. The chief complaints are vague and generally manifest over time; they include the following:

  • Fatigue

  • Shortness of breath

  • Increased abdominal girth

  • Weight gain/weight loss

  • Nonproductive cough

  • Bloating

  • Amenorrhea for premenopausal women

  • Menstrual irregularity


Physical Examination

Positive signs of Meigs syndrome include the following:

  • Vital signs - Tachypnea, tachycardia

  • Lungs - Dullness to percussion; decreased tactile fremitus; decreased vocal resonance; decreased breath sounds, suggesting pleural effusion, which is mostly observed on the right side but can also be left sided

  • Abdomen - Most patients present with an asymptomatic, solid, and unilateral pelvic mass, most often left sided; the mass may be large, [7]  but sometimes, no mass is felt; ascites is present, with shifting dullness and/or fluid thrill

  • Pelvis - Examination reveals a pelvic mass