Meigs Syndrome Treatment & Management

Updated: Feb 19, 2021
  • Author: Klaus-Dieter Lessnau, MD, FCCP; Chief Editor: Leslie M Randall, MD, MAS, FACS  more...
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Medical Care

Medical care of patients with Meigs syndrome is intended to provide symptomatic relief of ascites and pleural effusion by means of therapeutic paracentesis and thoracentesis.


Consult with a gynecologic surgeon for surgical management of the patient.

Consult with a pulmonologist for management of pleural effusion. Medical pleuroscopy is typically not indicated but may be useful in complicated patients.


Patients can maintain activities as tolerated.


Surgical Care

Note the following:

  • Resolution after tumor resection has been widely documented.   [3, 18, 10]

  • Exploratory laparotomy with surgical staging is the treatment of choice. Perform a frozen section of the ovarian mass during exploratory laparotomy. If the frozen section is consistent with benign tumor, conservative surgery (salpingo-oophorectomy or oophorectomy) is appropriate. Findings of lymph node biopsies and omentum and pelvic washings are negative for malignancy if these procedures are performed during surgery.

  • In women of reproductive age, perform unilateral salpingo-oophorectomy.

  • In postmenopausal women, options include bilateral salpingo-oophorectomy with total hysterectomy and unilateral or occasionally bilateral salpingo-oophorectomy.

  • In prepubertal girls, options include wedge resection of ovary and unilateral salpingo-oophorectomy.

  • The cure rate after either type of surgery is high and recurrence is rare.

Observe standard postsurgical management protocols.