Abnormal (Dysfunctional) Uterine Bleeding Questions & Answers

Updated: Mar 29, 2022
  • Author: Thomas Michael Price, MD; Chief Editor: Richard Scott Lucidi, MD, FACOG  more...
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Questions & Answers

Overview

What is abnormal uterine bleeding (AUB)?

How frequently do women with abnormal uterine bleeding (AUB) develop endometrial cancer?

What are the signs and symptoms of abnormal uterine bleeding (AUB)?

What is included in the workup of abnormal uterine bleeding (AUB)?

Which medications are used in the treatment of abnormal uterine bleeding (AUB)?

When is hysterectomy indicated in the treatment of abnormal uterine bleeding (AUB)?

When is endometrial ablation indicated in the treatment of abnormal uterine bleeding (AUB)?

How is abnormal uterine bleeding (AUB) diagnosed?

What is the role of cyclic endometrial stimulation in the pathophysiology of abnormal uterine bleeding (AUB)?

What is the prevalence of abnormal uterine bleeding?

Which age groups have the highest prevalence of abnormal uterine bleeding?

What is the morbidity associated with abnormal uterine bleeding (AUB)?

What is included in patient education about abnormal uterine bleeding (AUB)?

How is normal uterine bleeding differentiated from abnormal uterine bleeding (AUB)?

What is estrogen breakthrough bleeding?

What is estrogen withdrawal bleeding?

What is the role of oral contraceptives and steroid replacement therapy in the etiology of abnormal uterine bleeding (AUB)?

What causes abnormal uterine bleeding (AUB) in adolescent girls?

What causes abnormal uterine bleeding (AUB) during menopause?

When should an underlying bleeding disorder be considered as the cause of abnormal uterine bleeding (AUB)?

Presentation

Which clinical history findings are characteristic of abnormal uterine bleeding (AUB)?

What is included in the physical exam to evaluate abnormal uterine bleeding (AUB)?

DDX

Why is endometrial sampling included in the workup of abnormal uterine bleeding (AUB)?

What are the possible complications of the surgery for abnormal uterine bleeding (AUB)?

Which conditions are included in the differential diagnoses of abnormal uterine bleeding (AUB)?

What are the differential diagnoses for Abnormal (Dysfunctional) Uterine Bleeding?

Workup

Which lab tests are performed in the workup of abnormal uterine bleeding (AUB)?

What is the role of human chorionic gonadotropin testing in the workup of abnormal uterine bleeding (AUB)?

What is the role of CBC count in the workup of abnormal uterine bleeding (AUB)?

What is the role of PAP smear in the workup of abnormal uterine bleeding (AUB)?

When is endometrial sampling indicated in the workup of abnormal uterine bleeding (AUB)?

What is the role of thyroid and liver function tests in the workup of abnormal uterine bleeding (AUB)?

What is the role of coagulation studies in the workup of abnormal uterine bleeding (AUB)?

What is the role of hormone studies in the workup of abnormal uterine bleeding (AUB)?

What is the role of imaging studies in the workup of abnormal uterine bleeding (AUB)?

When is endometrial carcinoma included in the differential diagnoses of abnormal uterine bleeding (AUB) and how is it ruled out?

Treatment

What are the ACOG guidelines on the treatment of abnormal uterine bleeding (AUB)?

What are the medical treatments for abnormal uterine bleeding (AUB)?

What is the role of oral contraceptives in the treatment of abnormal uterine bleeding (AUB)?

What is the role of estrogen in the treatment of abnormal uterine bleeding (AUB)?

What is the role of progestins in the treatment of abnormal uterine bleeding (AUB)?

What is the role of desmopressin in the treatment of abnormal uterine bleeding (AUB)?

When is surgery indicated in the treatment of abnormal uterine bleeding (AUB)?

What is the role of D&C in the treatment of abnormal uterine bleeding (AUB)?

What is the role of hysterectomy in the treatment of abnormal uterine bleeding (AUB)?

What is the role of endometrial ablation in the treatment of abnormal uterine bleeding (AUB)?

Medications

What is the role of medications in the treatment of abnormal uterine bleeding (AUB)?

Which medications in the drug class Gonadotropin Releasing Hormone Antagonists are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class GnRH agonists are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Nonsteroidal anti-inflammatory drugs are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Androgens are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Combination oral contraceptives are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Progestins are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Estrogens are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Antifibrinolytic Agents are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?

Which medications in the drug class Arginine vasopressin derivatives are used in the treatment of Abnormal (Dysfunctional) Uterine Bleeding?