Malignant Lesions of the Fallopian Tube and Broad Ligament Clinical Presentation

Updated: Jan 24, 2019
  • Author: Hetal B Gor, MD, FACOG; Chief Editor: Warner K Huh, MD  more...
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Presentation

History

Malignant lesions of the fallopian tube

Patients may present with pelvic pain, a pelvic mass, postmenopausal bleeding, and serosanguineous vaginal discharge.

The classic description of hydrops tubae profluens, which is characterized by colicky lower abdominal pain relieved by a profuse, serous, watery, yellow, intermittent, vaginal discharge, usually is not found.

Malignant lesions of the broad ligament

A clinical history of vague abdominal pain may be present. Upon examination or with abdominal exploration, an adnexal mass is found.

Rarely, it can manifest as an acute abdominal emergency, simulating appendicitis.

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Physical

Physical examination findings are not specific; a pelvic mass usually is present, with or without ascites.

Diagnostic criteria include the following:

  • Grossly, the main tumor should be in the fallopian tube.

  • Histologically, the tubal mucosa should be involved, with a papillary pattern.

  • The tubal wall, if involved, and a transition from benign to malignant tubal epithelium should be identified.

  • The lesion is a more advanced stage of tubal tumor than the other tumors.

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Causes

The exact etiology is unknown.

Infertility and chronic salpingitis were believed to lead to an increase in incidence, but this theory has not been proven. However, malignancy has been associated with tuberculous salpingitis.

Similar to ovarian malignancy, a BRCA germline mutation and TP53 mutation are associated with fallopian tube malignancy. [4]

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