Angiosarcoma Questions & Answers

Updated: Sep 04, 2018
  • Author: Maria Belén Carsi, MD, PhD, FRCS; Chief Editor: Edwin Choy, MD, PhD  more...
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Questions & Answers

Overview

What is angiosarcoma (AS)?

What is the pathophysiology of an angiosarcoma (AS)?

What is the prevalence of angiosarcoma (AS) in the US?

What is the global prevalence of angiosarcoma (AS)?

What are the mortality rates for angiosarcoma (AS)?

Which patient groups are at highest risk for angiosarcoma (AS)?

Presentation

Which is the focus of the clinical history for angiosarcoma (AS)?

What are the risk factors for angiosarcoma (AS)?

What are the signs and symptoms of angiosarcoma (AS)?

What causes angiosarcoma (AS)?

What is the role of radical mastectomy in the etiology of angiosarcoma (AS)?

What is the role of radiotherapy in the etiology of angiosarcoma (AS)?

Which foreign material in the body may cause angiosarcoma (AS)?

What is the role of environmental carcinogens in the etiology of angiosarcoma (AS)?

Which physical findings are characteristic of angiosarcoma (AS)?

Which physical findings are characteristic of soft tissue angiosarcoma (AS)?

Which physical findings are characteristic of angiosarcoma (AS) of bone?

What are the variants of cutaneous angiosarcoma (AS)?

Which physical findings are characteristic of angiosarcoma (AS) of the scalp and face?

Which clinical history findings are characteristic of lymphedema-associated angiosarcoma (LAS)?

Which clinical history findings are characteristic of radiation-induced angiosarcoma (AS)?

Which clinical history findings are characteristic of epithelioid angiosarcoma (AS)?

DDX

Which conditions should be considered in the differential diagnoses of angiosarcoma (AS)?

What are the differential diagnoses for Angiosarcoma?

Workup

What is the role of lab testing in the diagnosis of angiosarcoma (AS)?

What is the role of imaging studies in the diagnosis of soft tissue angiosarcoma (AS)?

What is the role of imaging studies in the diagnosis of bone angiosarcoma (AS)?

What is the role of imaging studies in the diagnosis of cutaneous angiosarcoma (AS)?

Which histologic findings are characteristic of angiosarcoma (AS)?

What is the role of immunohistochemical staining in the diagnosis of angiosarcoma (AS)?

How is angiosarcoma (AS) staged?

What are the stages of bone and soft tissue angiosarcoma (AS)?

What is the role of biopsy in the diagnosis of angiosarcoma (AS)?

Treatment

What are the NCCN treatment guidelines for soft-tissue angiosarcoma (AS)?

What is the efficacy of chemotherapy for the treatment of soft-tissue angiosarcoma (AS)?

What is the role of radiotherapy in the treatment of soft-tissue angiosarcoma (AS)?

How is bone angiosarcoma (AS) treated?

How is cutaneous angiosarcoma (AS) treated?

What is the role of surgery in the treatment of soft-tissue angiosarcoma (AS)?

What is the role of surgery in the treatment of angiosarcoma (AS) of bone?

What is the role of surgery in the treatment of cutaneous angiosarcoma (AS)?

Medications

What is the goal of drug treatment for angiosarcoma (AS)?

Which medications in the drug class Antineoplastic agents are used in the treatment of Angiosarcoma?

Follow-up

What is included in long-term monitoring of soft-tissue and bone angiosarcoma (AS)?

What is the role of MRI in the long-term monitoring of angiosarcoma (AS)?

What is included in long-term monitoring of cutaneous angiosarcoma (AS)?

What is included in inpatient care for angiosarcoma (AS)?

How is angiosarcoma (AS) prevented?

What are the possible complications from radiotherapy for angiosarcoma (AS)?

What are the possible complications from chemotherapy for angiosarcoma (AS)?

What are the possible complications from surgery for angiosarcoma (AS)?

What is the prognosis of soft-tissue angiosarcoma (AS)?

What is the prognosis of bone angiosarcoma (AS)?

What is the prognosis of cutaneous angiosarcoma (AS)?

What is included in patient education about angiosarcoma (AS)?