Cardiac Sarcoma Clinical Presentation

Updated: Sep 21, 2023
  • Author: John H Raaf, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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No typical presentation of cardiac sarcoma exists because the common symptoms and signs are nonspecific. However, patients may complain of dyspnea, chest pain, and/or generalized fatigue.



Cardiac sarcoma has no pathognomonic physical features that may be discovered on examination. However, the following signs may accompany cardiac sarcoma:

  • Dyspnea
  • Hemoptysis
  • Diminished cardiac sounds
  • Friction rub
  • Rales
  • Refractory arrhythmias
  • Heart block
  • Heart failure

An audible plop due to tumor prolapse through the mitral valve may be appreciated.

Left-sided embolization may lead to cerebrovascular accident, peripheral organ infarction, seizures, and distant metastases.

Upper extremity and facial congestion (suggestive of superior vena cava syndrome) and dysphonia may occur.