Cardiac Sarcoma Differential Diagnoses

1. Shanmugam G. Primary cardiac sarcoma. Eur J Cardiothorac Surg. 2006 Jun. 29(6):925-32. [QxMD MEDLINE Link].

2. Neragi-Miandoab S, Kim J, Vlahakes GJ. Malignant tumours of the heart: a review of tumour type, diagnosis and therapy. Clin Oncol (R Coll Radiol). 2007 Dec. 19(10):748-56. [QxMD MEDLINE Link].

3. Barreiro M, Renilla A, Jimenez JM, Martin M, Al Musa T, Garcia L, et al. Primary cardiac tumors: 32 years of experience from a Spanish tertiary surgical center. Cardiovasc Pathol. 2013 May 30. [QxMD MEDLINE Link].

4. Travis WD, Brambilla E, Burke AP, Marx A, Nicholson AG (Eds.). WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. 4th Edition. Lyon, France: International Agency for Research on Cancer; 2015.

5. Zu Y, Perle MA, Yan Z. Chromosomal abnormalities and p53 gene mutation in a cardiac angiosarcoma. Appl Immunohistochem Mol Morphol. 2001 Mar. 9(1):24-8. [QxMD MEDLINE Link].

6. Burke A, Tavora F. The 2015 WHO Classification of Tumors of the Heart and Pericardium. J Thorac Oncol. 2016 Apr. 11 (4):441-52. [QxMD MEDLINE Link]. [Full Text].

7. Isogai T, Yasunaga H, Matsui H, Tanaka H, Hisagi M, Fushimi K. Factors affecting in-hospital mortality and likelihood of undergoing surgical resection in patients with primary cardiac tumors. J Cardiol. 2017 Jan. 69 (1):287-292. [QxMD MEDLINE Link]. [Full Text].

8. Simpson L, Kumar SK, Okuno SH, Schaff HV, Porrata LF, Buckner JC, et al. Malignant primary cardiac tumors: review of a single institution experience. Cancer. 2008 Jun. 112(11):2440-6. [QxMD MEDLINE Link].

9. Randhawa JS, Budd GT, Randhawa M, Ahluwalia M, Jia X, Daw H, et al. Primary Cardiac Sarcoma: 25-Year Cleveland Clinic Experience. Am J Clin Oncol. 2016 Dec. 39 (6):593-599. [QxMD MEDLINE Link].

10. Yuan SM, Shinfeld A, Lavee J, Kuperstein R, Haizler R, Raanani E. Imaging morphology of cardiac tumours. Cardiol J. 2009. 16(1):26-35. [QxMD MEDLINE Link].

11. Meng Q, Lai H, Lima J. Echocardiographic and pathologic characteristics of primary cardiac tumors: a study of 149 cases. Int J Cardiol. 2002 Jul. 84(1):69-75. [QxMD MEDLINE Link].

12. Randhawa K, Ganeshan A, Hoey ET. Magnetic resonance imaging of cardiac tumors: part 1, sequences, protocols, and benign tumors. Curr Probl Diagn Radiol. 2011 Jul-Aug. 40(4):158-68. [QxMD MEDLINE Link].

13. Randhawa K, Ganeshan A, Hoey ET. Magnetic resonance imaging of cardiac tumors: part 2, malignant tumors and tumor-like conditions. Curr Probl Diagn Radiol. 2011 Jul-Aug. 40(4):169-79. [QxMD MEDLINE Link].

14. Fussen S, De Boeck BW, Zellweger MJ, et al. Cardiovascular magnetic resonance imaging for diagnosis and clinical management of suspected cardiac masses and tumours. Eur Heart J. 2011 Jun. 32(12):1551-60. [QxMD MEDLINE Link].

15. Schur S, Hamacher R, Brodowicz T. Pazopanib in Primary Cardiac Angiosarcoma of the Right Atrium: A Case Report. Case Rep Oncol. 2016 May-Aug. 9 (2):363-7. [QxMD MEDLINE Link]. [Full Text].

16. Collins CL, Bartz PJ, Lal DR, Segura AD, Woods RK, Tower RL 2nd. Significant Response to Oral Etoposide in the Treatment of an Unresectable Cardiac Sarcoma. J Pediatr Hematol Oncol. 2013 May 3. [QxMD MEDLINE Link].

17. Abu Saleh WK, Ramlawi B, Shapira OM, Al Jabbari O, Ravi V, Benjamin R, et al. Improved Outcomes With the Evolution of a Neoadjuvant Chemotherapy Approach to Right Heart Sarcoma. Ann Thorac Surg. 2017 Jul. 104 (1):90-96. [QxMD MEDLINE Link].

18. Reardon MJ, Walkes JC, Benjamin R. Therapy insight: malignant primary cardiac tumors. Nat Clin Pract Cardiovasc Med. 2006 Oct. 3(10):548-53. [QxMD MEDLINE Link].

19. Furukawa N, Gummert J, Börgermann J. Complete resection of undifferentiated cardiac sarcoma and reconstruction of the atria and the superior vena cava: case report. J Cardiothorac Surg. 2012 Sep 27. 7:96. [QxMD MEDLINE Link]. [Full Text].

20. Gowdamarajan A, Michler RE. Therapy for primary cardiac tumors: is there a role for heart transplantation?. Curr Opin Cardiol. 2000 Mar. 15(2):121-5. [QxMD MEDLINE Link].

21. Grandmougin D, Fayad G, Decoene C. Total orthotopic heart transplantation for primary cardiac rhabdomyosarcoma: factors influencing long-term survival. Ann Thorac Surg. 2001 May. 71(5):1438-41. [QxMD MEDLINE Link].

22. Jimenez Mazuecos JM, Fuentes Manso R, Segovia Cubero J, Toquero Ramos J, Oteo Domínguez JF, Alonso-Pulpon Rivera L, et al. [Is heart transplantation for primary cardiac sarcoma a useful therapeutic option?]. Rev Esp Cardiol. 2003 Apr. 56(4):408-11. [QxMD MEDLINE Link].

23. Uberfuhr P, Meiser B, Fuchs A. Heart transplantation: an approach to treating primary cardiac sarcoma?. J Heart Lung Transplant. 2002 Oct. 21(10):1135-9. [QxMD MEDLINE Link].

24. Li H, Yang S, Chen H, Yang Z, Hong T, Hou Y, et al. Survival after heart transplantation for non-metastatic primary cardiac sarcoma. J Cardiothorac Surg. 2016 Oct 3. 11 (1):145. [QxMD MEDLINE Link].

25. Hoffmeier A, Deiters S, Schmidt C. Radical resection of cardiac sarcoma. Thorac Cardiovasc Surg. 2004 Apr. 52(2):77-81. [QxMD MEDLINE Link].

26. Hoffmeier A, Scheld HH, Tjan TD. Ex situ resection of primary cardiac tumors. Thorac Cardiovasc Surg. 2003 Apr. 51(2):99-101. [QxMD MEDLINE Link].

27. Blackmon SH, Patel AR, Bruckner BA, Beyer EA, Rice DC, Vaporciyan AA, et al. Cardiac autotransplantation for malignant or complex primary left-heart tumors. Tex Heart Inst J. 2008. 35(3):296-300. [QxMD MEDLINE Link].

John H Raaf, MD, PhD (Retired) Professor, Department of Surgery, Case Western Reserve University School of Medicine

John H Raaf, MD, PhD is a member of the following medical societies: American Association for Cancer Research, American College of Surgeons, Central Surgical Association, Society of Surgical Oncology, American Association of Endocrine Surgeons, American Society of Clinical Oncology

Disclosure: Nothing to disclose.

Anastasios K Konstantakos, MD Clinical Associate Surgeon, Department of Cardiovascular Surgery, Billings Clinic

Disclosure: Nothing to disclose.

Heather N Raaf, MD (Retired) Chief Deputy Coroner, Cuyahoga County Coroner's Office

Heather N Raaf, MD is a member of the following medical societies: National Association of Medical Examiners, American Academy of Forensic Sciences

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Eric H Yang, MD Associate Professor of Medicine, Director of Cardiac Catherization Laboratory and Interventional Cardiology, Mayo Clinic ArizonA

Eric H Yang, MD is a member of the following medical societies: Alpha Omega Alpha

Disclosure: Nothing to disclose.

Robert C Shepard, MD, FACP Associate Professor of Medicine in Hematology and Oncology at University of North Carolina at Chapel Hill; Vice President of Scientific Affairs, Therapeutic Expertise, Oncology, at PRA International

Robert C Shepard, MD, FACP is a member of the following medical societies: American Association for Cancer Research, American Association for Physician Leadership, European Society for Medical Oncology, Association of Clinical Research Professionals, American Federation for Clinical Research, Eastern Cooperative Oncology Group, Society for Immunotherapy of Cancer, American Medical Informatics Association, American College of Physicians, American Federation for Medical Research, American Medical Association, American Society of Hematology, Massachusetts Medical Society

Disclosure: Nothing to disclose.

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