Cardiac Sarcoma Treatment & Management

Updated: Oct 15, 2015
  • Author: John H Raaf, MD, PhD; Chief Editor: Eric H Yang, MD  more...
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Medical Care

A case was reported for which preoperative chemotherapy reduced the size of an unresectable undifferentiated cardiac sarcoma, so that residual tumor could then be completely resected. [13]


Surgical Care

Cardiac sarcoma is rarely cured, but prolonged survival or significant palliation is possible with surgical resection. [14, 15] Exploration with biopsy yields tissue for histologic diagnosis and assessment of the gross extent of the tumor.

The role of orthotopic heart transplantation for malignant cardiac tumors continues to be debated. [16, 17, 18, 19]

Bench surgery (explantation and autotransplantation of the heart) may aid in achieving more complete tumor resection. [20, 21, 22]

Complete or partial excision of primary or metastatic cardiac sarcoma can provide hemodynamic improvement and relief from congestive heart failure. Alternatively, a pericardial window or pericardiectomy may ameliorate symptoms.

Postsurgical adjuvant radiation and chemotherapy have not proven consistently beneficial. However, adjuvant radiation or chemotherapy can be beneficial in ameliorating symptoms and improving quality of life.



Cardiothoracic surgeon and/or oncologist