Cholangiocarcinoma Questions & Answers

Updated: Aug 30, 2018
  • Author: Peter E Darwin, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Questions & Answers

Overview

What is cholangiocarcinoma (CCC)?

What are the common types of cholangiocarcinoma (CCC)?

What are the treatment options for cholangiocarcinoma (CCC)?

What is the pathophysiology of cholangiocarcinoma (CCC)?

What is the prevalence of cholangiocarcinoma (CCC) in the US?

What is the global incidence of cholangiocarcinoma (CCC)?

What is the mortality rate for cholangiocarcinoma (CCC)?

What are the racial predilections for cholangiocarcinoma (CCC)?

How does the incidence of cholangiocarcinoma (CCC) vary by sex and age?

Presentation

What are the signs and symptoms of cholangiocarcinoma (CCC)?

Which physical findings are characteristic of cholangiocarcinoma (CCC)?

What causes cholangiocarcinoma (CCC)?

What is the role of infections in the etiology of cholangiocarcinoma (CCC)?

What is the role of inflammatory bowel disease in the etiology of cholangiocarcinoma (CCC)?

What is the role of chemical exposures in the etiology of cholangiocarcinoma (CCC)?

Which congenital conditions are associated with cholangiocarcinoma (CCC)?

DDX

What are the differential diagnoses for Cholangiocarcinoma?

Workup

What is the role of lab studies in the workup of cholangiocarcinoma (CCC)?

What is the role of tumor markers in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of imaging studies in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of ultrasonography in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of CT scanning in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of MRI in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of positron emission tomography (PET) in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of endoscopic ultrasonography (EUS) in the diagnosis of cholangiocarcinoma (CCC)?

What is the role of endoscopic retrograde cholangiopancreatography (ERCP) in the workup of cholangiocarcinoma (CCC)?

What is the role of percutaneous transhepatic cholangiography (PTC) in the workup of cholangiocarcinoma (CCC)?

Which histologic findings are characteristic of cholangiocarcinoma (CCC)?

How is cholangiocarcinoma (CCC) staged?

What are the staging classifications for intrahepatic bile duct tumors in cholangiocarcinoma (CCC)?

What are the staging classifications for perihilar bile duct tumors in cholangiocarcinoma (CCC)?

What are the staging classifications for distal bile duct tumors in cholangiocarcinoma (CCC)?

What is the role of angiography in the diagnosis of cholangiocarcinoma (CCC)?

Treatment

What are the treatment options for cholangiocarcinoma (CCC)?

What are palliative treatment options for cholangiocarcinoma (CCC)?

What is the role of stenting in the treatment of cholangiocarcinoma (CCC)?

What is the role of photodynamic therapy in the treatment of cholangiocarcinoma (CCC)?

What is the role of radiation therapy in the treatment of cholangiocarcinoma (CCC)?

What is the efficacy of radiotherapy for the treatment of cholangiocarcinoma (CCC)?

What is the role of chemotherapy in the management of cholangiocarcinoma (CCC)?

What is the role of surgery in the treatment of cholangiocarcinoma (CCC)?

Which specialist consultations are needed for the treatment of cholangiocarcinoma (CCC)?

Guidelines

What are the diagnostic guidelines for cholangiocarcinoma (CCC)?

What is the tumor-node-metastasis (TNM) classification of the American Joint Cancer Committee/Union for International Cancer Control/ (AJCC/UICC) for cholangiocarcinoma (CCC)?

What are the treatment guidelines for cholangiocarcinoma (CCC)?

Follow-up

How are adverse effects of therapy managed in patients with cholangiocarcinoma (CCC)?

What are the complications associated with cholangiocarcinoma (CCC)?

What is the prognosis of cholangiocarcinoma (CCC)?