Kaposi Sarcoma Questions & Answers

Updated: Apr 11, 2019
  • Author: Jessica Katz, MD, PhD; Chief Editor: Edwin Choy, MD, PhD  more...
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Questions & Answers

Overview

What is Kaposi sarcoma (KS)?

What are the signs and symptoms of Kaposi sarcoma (KS)?

How does classic Kaposi sarcoma (KS) differ from AIDS-related KS?

What is included in the workup of Kaposi sarcoma (KS)?

What types of therapies are used to treat Kaposi sarcoma (KS)?

What are the types of Kaposi sarcoma (KS)?

What is AIDS-related (epidemic) Kaposi sarcoma (KS)?

What is iatrogenic (immunosuppression-related) Kaposi sarcoma (KS)?

What is classic (sporadic) Kaposi sarcoma (KS)?

What is endemic African Kaposi sarcoma (KS)?

What is the pathophysiology of Kaposi sarcoma (KS)?

What is the role of cofactors in the pathophysiology of Kaposi sarcoma (KS)?

How is Kaposi sarcoma human herpes virus (KSHV) transmitted?

What are the racial predilections of Kaposi sarcoma (KS)?

What are the sexual predilections of Kaposi sarcoma (KS)?

Which age groups have the highest prevalence of Kaposi sarcoma (KS)?

What is the prevalence of Kaposi sarcoma (KS)?

What is the global prevalence of Kaposi sarcoma (KS)?

What is the morbidity and mortality associated with Kaposi sarcoma (KS)?

Presentation

Which clinical history findings are characteristic of Kaposi sarcoma (KS)?

Which physical findings are characteristic of Kaposi sarcoma (KS)?

What causes Kaposi sarcoma (KS)?

DDX

How is bacillary angiomatosis differentiated from Kaposi sarcoma (KS)?

Which conditions are included in the differential diagnoses of Kaposi sarcoma (KS)?

What are the differential diagnoses for Kaposi Sarcoma?

Workup

What is the role of lab tests in the workup of Kaposi sarcoma (KS)?

What is the role of chest radiographs in the workup of Kaposi sarcoma (KS)?

What is the role of nuclear imaging in the workup of Kaposi sarcoma (KS)?

What is the role of CT and PET/CT in the workup of Kaposi sarcoma (KS)?

What is the role of biopsy in the workup of Kaposi sarcoma (KS)?

What is the role of bronchoscopy in the workup of Kaposi sarcoma (KS)?

What is the role of EGD or colonoscopy in the workup of Kaposi sarcoma (KS)?

Which histologic findings are characteristic of Kaposi sarcoma (KS)?

How is Kaposi sarcoma (KS) staged?

Treatment

How is Kaposi sarcoma (KS) treated?

What is the role of antiretroviral therapy in the treatment of Kaposi sarcoma (KS)?

What is the role of chemotherapy in the treatment of Kaposi sarcoma (KS)?

What is the role of interferon-alfa in the treatment of Kaposi sarcoma (KS)?

What is the role of thalidomide in the treatment of Kaposi sarcoma (KS)?

What is the role of bevacizumab in the treatment of Kaposi sarcoma (KS)?

Which medications are under investigation for the treatment of Kaposi sarcoma (KS)?

When are local therapies indicated in the treatment of Kaposi sarcoma (KS)?

What is the role of radiation therapy in the treatment of Kaposi sarcoma (KS)?

What is the role of surgery in the treatment of Kaposi sarcoma (KS)?

What is the role of intralesional chemotherapy in the treatment of Kaposi sarcoma (KS)?

What is the role of cryotherapy in the treatment of Kaposi sarcoma (KS)?

What is the role of laser therapy in the treatment of Kaposi sarcoma (KS)?

What is the role of topical medications in the treatment of Kaposi sarcoma (KS)?

Which specialist consultations are beneficial to patients with Kaposi sarcoma (KS)?

What are the possible complications of Kaposi sarcoma (KS)?

How is Kaposi sarcoma (KS) prevented?

What is included in the long-term monitoring of Kaposi sarcoma (KS)?

Medications

What is the role of medication in the treatment of Kaposi sarcoma (KS)?

Which medications in the drug class Vinca alkaloids are used in the treatment of Kaposi Sarcoma?

Which medications in the drug class Retinoids are used in the treatment of Kaposi Sarcoma?

Which medications in the drug class Interferons are used in the treatment of Kaposi Sarcoma?

Which medications in the drug class Anthracyclines are used in the treatment of Kaposi Sarcoma?

Which medications in the drug class Taxanes are used in the treatment of Kaposi Sarcoma?