Primary Hepatic Carcinoma Questions & Answers

Updated: Feb 21, 2018
  • Author: Keith E Stuart, MD; Chief Editor: N Joseph Espat, MD, MS, FACS  more...
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Questions & Answers

Overview

What is primary hepatocellular carcinoma (HCC)?

What is the pathophysiology of primary hepatocellular carcinoma (HCC)?

What is the role of cirrhosis in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of hepatitis C infection in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of hemochromatosis in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of obesity in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of alcohol in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of hepatitis B infection in the etiology of primary hepatocellular carcinoma (HCC)?

What is the role of aflatoxin in the etiology of primary hepatocellular carcinoma (HCC)?

What are rare causes of primary hepatocellular carcinoma (HCC)?

What is the prevalence of primary hepatocellular carcinoma (HCC)?

What is the global prevalence of primary hepatocellular carcinoma (HCC)?

What are the racial predilections of primary hepatocellular carcinoma (HCC)?

What are the sexual predilections of primary hepatocellular carcinoma (HCC)?

At what age is primary hepatocellular carcinoma (HCC) typically diagnosed?

What is the prognosis of primary hepatocellular carcinoma (HCC)?

Presentation

What are the signs and symptoms of primary hepatocellular carcinoma (HCC)?

Which physical findings are characteristic of primary hepatocellular carcinoma (HCC)?

DDX

Which conditions are included in the differential diagnoses of primary hepatocellular carcinoma (HCC)?

What are the differential diagnoses for Primary Hepatic Carcinoma?

Workup

What is the role of lab testing in the workup of primary hepatocellular carcinoma (HCC)?

What is the role of imaging studies in the workup of primary hepatocellular carcinoma (HCC)?

What is the role of biopsy in the workup of primary hepatocellular carcinoma (HCC)?

Which histologic findings are characteristic of primary hepatocellular carcinoma (HCC)?

What are the TNM staging criteria for primary hepatocellular carcinoma (HCC)?

What are the stage groupings for primary hepatocellular carcinoma (HCC)?

How is primary hepatocellular carcinoma (HCC) staged?

What is the CLIP scoring system for primary hepatocellular carcinoma (HCC)?

What is the Barcelona Clinic Liver Cancer (BCLC) staging system for primary hepatocellular carcinoma (HCC)?

What is the efficacy of primary hepatocellular carcinoma (HCC) screening for at-risk patients?

Treatment

How is primary hepatocellular carcinoma (HCC) treated?

What is the role of chemotherapy in the treatment of primary hepatocellular carcinoma (HCC)?

What is the role of antiangiogenic therapy in the treatment of primary hepatocellular carcinoma (HCC)?

What is the role of immunotherapy in the treatment of primary hepatocellular carcinoma (HCC)?

How is partial hepatectomy performed for the treatment of primary hepatocellular carcinoma (HCC)?

What is the role of liver transplantation in the treatment of primary hepatocellular carcinoma (HCC)?

What is the role of locally ablative therapy in the treatment of primary hepatocellular carcinoma (HCC)?

Which specialist consultations are beneficial to patients with primary hepatocellular carcinoma (HCC)?

Which dietary modifications are used in the treatment of primary hepatocellular carcinoma (HCC)?

How is primary hepatocellular carcinoma (HCC) prevented?

What is included in the long-term monitoring of primary hepatocellular carcinoma (HCC)?

Guidelines

Which organizations have released clinical guidelines on primary hepatocellular carcinoma (HCC)?

What are the screening guidelines for primary hepatocellular carcinoma (HCC)?

What are the staging guidelines for primary hepatocellular carcinoma (HCC)?

What are the treatment guidelines for primary hepatocellular carcinoma (HCC)?

Medications

What is the role of medications in the treatment of primary hepatocellular carcinoma (HCC)?

Which medications in the drug class Antineoplastics, Monoclonal Antibody are used in the treatment of Primary Hepatic Carcinoma?

Which medications in the drug class Immunosuppressant agents are used in the treatment of Primary Hepatic Carcinoma?

Which medications in the drug class Antineoplastic agents are used in the treatment of Primary Hepatic Carcinoma?