Anderson P. WHO Reports 3 Million Alcohol-Related Deaths in 2016. Medscape Medical News. Available at https://www.medscape.com/viewarticle/902614. September 27, 2018; Accessed: October 2, 2018.
Poznyak V, Rekve D. Global status report on alcohol and health 2018. World Health Organization. September 21, 2018. Available at http://www.who.int/substance_abuse/publications/global_alcohol_report/gsr_2018/en/.
Sacks JJ, Gonzales KR, Bouchery EE, Tomedi LE, Brewer RD. 2010 National and State Costs of Excessive Alcohol Consumption. Am J Prev Med. 2015 Nov. 49 (5):e73-9. [Medline].
Substance Abuse and Mental Health Services Administration. Center for Substance Abuse Treatment. The Role of Biomarkers in the Treatment of Alcohol Use Disorders. US Department of Health and Human Services. September 2006. Available at http://kap.samhsa.gov/products/manuals/advisory/pdfs/0609_biomarkers.pdf.
Das SK, Dhanya L, Vasudevan DM. Biomarkers of alcoholism: an updated review. Scand J Clin Lab Invest. 2008. 68(2):81-92. [Medline]. [Full Text].
Niemelä O. Biomarkers in alcoholism. Clin Chim Acta. 2007 Feb. 377(1-2):39-49. [Medline].
Peterson K. Biomarkers for alcohol use and abuse. Alcohol Research & Health. 2004/2005. 28:
Substance Abuse and Mental Health Services Administration (SAMHSA). 2015 National Survey on Drug Use and Health (NSDUH). SAMHSA. Available at https://www.samhsa.gov/data/sites/default/files/NSDUH-DetTabs-2015/NSDUH-DetTabs-2015/NSDUH-DetTabs-2015.htm#tab2-46b. 2015; Accessed: September 12, 2017.
Vaillant GE. A long-term follow-up of male alcohol abuse. Arch Gen Psychiatry. 1996 Mar. 53(3):243-9. [Medline].
Lopez-Quintero C, Cobos JP, Hasin DS, et al. Probability and predictors of transition from first use to dependence on nicotine, alcohol, cannabis, and cocaine: Results of the National Epidemiologic Survey on Alcohol and Related Conditions (NESARC). Drug Alcohol Depend. 2011 May 1. 115(1-2):120-30. [Medline]. [Full Text].
CDC Press Release. Binge drinking is bigger problem than previously thought. Centers for Disease Control and Prevention. Available at http://www.cdc.gov/media/releases/2012/p0110_binge_drinking.html. Accessed: January 10, 2012.
Nutt DJ, King LA, Phillips LD. Drug harms in the UK: a multicriteria decision analysis. Lancet. 2010 Nov 6. 376(9752):1558-65. [Medline].
Doll R, Peto R, Boreham J, Sutherland I. Mortality in relation to alcohol consumption: a prospective study among male British doctors. Int J Epidemiol. 2005 Feb. 34(1):199-204. [Medline].
Knoops KT, de Groot LC, Kromhout D, Perrin AE, Moreiras-Varela O, Menotti A. Mediterranean diet, lifestyle factors, and 10-year mortality in elderly European men and women: the HALE project. JAMA. 2004 Sep 22. 292(12):1433-9. [Medline].
Thun MJ, Peto R, Lopez AD, et al. Alcohol consumption and mortality among middle-aged and elderly U.S. adults. N Engl J Med. 1997 Dec 11. 337(24):1705-14. [Medline].
Pletcher MJ, Varosy P, Kiefe CI, Lewis CE, Sidney S, Hulley SB. Alcohol consumption, binge drinking, and early coronary calcification: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Epidemiol. 2005 Mar 1. 161(5):423-33. [Medline].
Ruidavets JB, Ducimetiere P, Evans A, Montaye M, Haas B, Bingham A. Patterns of alcohol consumption and ischaemic heart disease in culturally divergent countries: the Prospective Epidemiological Study of Myocardial Infarction (PRIME). BMJ. 2010. 341:c6077. [Medline].
Sood B, Delaney-Black V, Covington C, et al. Prenatal alcohol exposure and childhood behavior at age 6 to 7 years: I. dose-response effect. Pediatrics. 2001 Aug. 108(2):E34. [Medline].
Baer JS, Sampson PD, Barr HM, et al. A 21-year longitudinal analysis of the effects of prenatal alcohol exposure on young adult drinking. Arch Gen Psychiatry. 2003 Apr. 60(4):377-85. [Medline].
Ault, A. Proven Screening Tool for Alcohol Abuse Underutilized. Medscape Medical News. Available at http://www.medscape.com/viewarticle/861116. March 29, 2016; Accessed: April 7, 2016.
Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, et al. Epidemiology of DSM-5 Alcohol Use Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions III. JAMA Psychiatry. 2015 Aug. 72 (8):757-66. [Medline].
Arria AM, Caldeira KM, Kasperski SJ, Vincent KB, Griffiths RR, O'Grady KE. Energy Drink Consumption and Increased Risk for Alcohol Dependence. Alcohol Clin Exp Res. 2010 Nov 12. [Medline].
Brauser D. New Guidelines for Alcohol Misuse in Adults Released. Medscape Medical News. Available at http://at http://www.medscape.com/viewarticle/804212.
Moyer VA; U.S. Preventive Services Task Force. Screening and Behavioral Counseling Interventions in Primary Care to Reduce Alcohol Misuse: U.S. Preventive Services Task Force Recommendation Statement. Ann Intern Med. 2013 May 14. doi:10.7326/0003-4819-159-3-201308060-00652. [Epub ahead of print].
Enoch MA, Goldman D. Problem drinking and alcoholism: diagnosis and treatment. Am Fam Physician. 2002 Feb 1. 65(3):441-8. [Medline].
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition. Washington, DC: American Psychiatric Association; 2013.
Spitzer RL, Kroenke K, Williams JB. Validation and utility of a self-report version of PRIME-MD: the PHQ primary care study. Primary Care Evaluation of Mental Disorders. Patient Health Questionnaire. JAMA. 1999 Nov 10. 282(18):1737-44. [Medline].
Boutin-Foster C, Ferrando SJ, Charlson ME. The Cornell Psychiatric Screen: a brief psychiatric scale for hospitalized medical patients. Psychosomatics. 2003 Sep-Oct. 44(5):382-7. [Medline].
Nery FG, Stanley JA, Chen HH, Hatch JP, Nicoletti MA, Serap Monkul E, et al. Bipolar disorder comorbid with alcoholism: A (1)H magnetic resonance spectroscopy study. J Psychiatr Res. 2009 Oct 7. [Medline]. [Full Text].
Hicks BM, Krueger RF, Iacono WG, McGue M, Patrick CJ. Family transmission and heritability of externalizing disorders: a twin-family study. Arch Gen Psychiatry. 2004 Sep. 61(9):922-8. [Medline].
Schuckit MA, Smith TL. An 8-year follow-up of 450 sons of alcoholic and control subjects. Arch Gen Psychiatry. 1996 Mar. 53(3):202-10. [Medline].
Chengappa KN, Levine J, Gershon S, Kupfer DJ. Lifetime prevalence of substance or alcohol abuse and dependence among subjects with bipolar I and II disorders in a voluntary registry. Bipolar Disord. 2000 Sep. 2(3 Pt 1):191-5. [Medline].
Jacobsen LK, Southwick SM, Kosten TR. Substance use disorders in patients with posttraumatic stress disorder: a review of the literature. Am J Psychiatry. 2001 Aug. 158(8):1184-90. [Medline].
Vlahov D, Galea S, Ahern J, Resnick H, Boscarino JA, Gold J. Consumption of cigarettes, alcohol, and marijuana among New York City residents six months after the September 11 terrorist attacks. Am J Drug Alcohol Abuse. 2004 May. 30(2):385-407. [Medline].
Marshall RD, Galea S. Science for the community: assessing mental health after 9/11. J Clin Psychiatry. 2004. 65 Suppl 1:37-43. [Medline].
Shipherd JC, Stafford J, Tanner LR. Predicting alcohol and drug abuse in Persian Gulf War veterans: what role do PTSD symptoms play?. Addict Behav. 2005 Mar. 30(3):595-9. [Medline].
Green B. Post-traumatic stress disorder: symptom profiles in men and women. Curr Med Res Opin. 2003. 19(3):200-4. [Medline].
Dobie DJ, Kivlahan DR, Maynard C, Bush KR, Davis TM, Bradley KA. Posttraumatic stress disorder in female veterans: association with self-reported health problems and functional impairment. Arch Intern Med. 2004 Feb 23. 164(4):394-400. [Medline].
de Beaurepaire R, Lukasiewicz M, Beauverie P, Castéra S, Dagorne O, Espaze R, et al. Comparison of self-reports and biological measures for alcohol, tobacco, and illicit drugs consumption in psychiatric inpatients. Journal of European Psychiatry. November 2007. 22 (8):540-548. [Medline].
Hannuksela ML, Liisanantti MK, Nissinen AE, Savolainen MJ. Biochemical markers of alcoholism. Clin Chem Lab Med. 2007. 45(8):953-61. [Medline]. [Full Text].
Sommers MS, Savage C, Wray J, Dyehouse JM. Laboratory measures of alcohol (ethanol) consumption: strategies to assess drinking patterns with biochemical measures. Biol Res Nurs. 2003 Jan. 4(3):203-17. [Medline].
Bergström JP, Helander A. Clinical Characteristics of Carbohydrate-Deficient Transferrin (%Disialotransferrin) Measured by HPLC: Sensitivity, Specificity, Gender Effects, and Relationship with other Alcohol Biomarkers. Alcohol Alcohol. 2008 Apr 24. [Medline].
Neumann T, Spies C. Use of biomarkers for alcohol use disorders in clinical practice. Addiction. 2003 Dec. 98 Suppl 2:81-91. [Medline].
Bean P. State of the art contemporary biomarkers of alcohol consumption. MLO Med Lab Obs. 2005 Nov. 37(11):10-2, 14, 16-7; quiz 18-9. [Medline].
Hietala J, Koivisto H, Anttila P, Niemelä O. Comparison of the combined marker GGT-CDT and the conventional laboratory markers of alcohol abuse in heavy drinkers, moderate drinkers and abstainers. Alcohol Alcohol. 2006 Sep-Oct. 41(5):528-33. [Medline].
Johnson BA. Medication treatment of different types of alcoholism. Am J Psychiatry. 2010 Jun. 167(6):630-9. [Medline].
US Preventive Services Task Force., Curry SJ, Krist AH, Owens DK, Barry MJ, Caughey AB, et al. Screening and Behavioral Counseling Interventions to Reduce Unhealthy Alcohol Use in Adolescents and Adults: US Preventive Services Task Force Recommendation Statement. JAMA. 2018 Nov 13. 320 (18):1899-1909. [Medline].
Reus VI, Fochtmann LJ, Bukstein O, Eyler AE, Hilty DM, Horvitz-Lennon M, et al. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder. Am J Psychiatry. 2018 Jan 1. 175 (1):86-90. [Medline].
Sinclair JD. Evidence about the use of naltrexone and for different ways of using it in the treatment of alcoholism. Alcohol Alcohol. 2001 Jan-Feb. 36(1):2-10. [Medline].
Rosner S, Hackl-Herrwerth A, Leucht S, Vecchi S, Srisurapanont M, Soyka M. Opioid antagonists for alcohol dependence. Cochrane Database Syst Rev. 2010 Dec 8. 12:CD001867. [Medline].
Cassels C. Anticonvulsant Promising for Alcohol Dependence. Medscape Medical News. Available at http://www.medscape.com/viewarticle/813817. Accessed: November 13, 2013.
Mason BJ, Quello S, Goodell V, Shadan F, Kyle M, Begovic A. Gabapentin Treatment for Alcohol Dependence: A Randomized Clinical Trial. JAMA Intern Med. 2013 Nov 4. [Medline].
Nunes EV. Gabapentin: A New Addition to the Armamentarium for Alcohol Dependence?. JAMA Intern Med. 2013 Nov 4. [Medline].
Davenport, L. Antibiotic Cuts Alcohol Cravings, May Enhance Psychotherapy. Medscape Medical News. Available at http://www.medscape.com/viewarticle/845066. Accessed: May 22, 2015.
MacKillop J, Few LR, Stojek MK, Murphy CM, Malutinok SF, Johnson FT, et al. D-cycloserine to enhance extinction of cue-elicited craving for alcohol: a translational approach. Transl Psychiatry. 2015 Apr 7. 5:e544. [Medline].
Pescosolido BA, Martin JK, Long JS, Medina TR, Phelan JC, Link BG. "A disease like any other"? A decade of change in public reactions to schizophrenia, depression, and alcohol dependence. Am J Psychiatry. 2010 Nov. 167(11):1321-30. [Medline].
CDC. Alcohol-Related Disease Impact (ARDI). Centers for Disease Control and Prevention. Available at http://nccd.cdc.gov/DPH_ARDI/default/default.aspx. Accessed: March 4, 2016.
Stahre M, Roeber J, Kanny D, Brewer RD, Zhang X. Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States. Prev Chronic Dis. 2014 Jun 26. 11:E109. [Medline].
World Health Organization. Global status report on alcohol and health. 2014. Available at http://www.who.int/substance_abuse/publications/global_alcohol_report/msb_gsr_2014_1.pdf?ua=1.
Saitz R. Clinical practice. Unhealthy alcohol use. N Engl J Med. 2005 Feb 10. 352(6):596-607. [Medline].
American Medical Association. Alcoholism in the elderly. Council on Scientific Affairs, American Medical Association. JAMA. 1996 Mar 13. 275(10):797-801. [Medline].
Anton RF, Moak DH, Waid LR, et al. Naltrexone and cognitive behavioral therapy for the treatment of outpatient alcoholics: results of a placebo-controlled trial. Am J Psychiatry. 1999 Nov. 156(11):1758-64. [Medline].
Bigby JA. Substance Abuse Education and General Internal Medicine: A Manual for Faculty. Washington, DC: Society of General Internal Medicine; 1993.
Brauser D. CDC Urges Physicians to Ask About Alcohol. Medscape Medical News. Available at http://www.medscape.com/viewarticle/818793. Accessed: January 16, 214.
Brauser D. Inflammatory Markers May Predict Alcohol Dependence. Medscape Medical News. Available at http://www.medscape.com/viewarticle/836307. Accessed: December 12, 2014.
Brooks M. Alcohol remains a leading cause of premature death. Medscape Medical News. June 27, 2014. [Full Text].
Brooks M. Binge Drinking Boosts Mortality Risk in Older Adults. Medscape Medical News. Mar 3 2014. [Full Text].
CDC. Alcohol Screening and Counseling: An effective but underused health service. Available. Medscape Medical News. Available at http://www.cdc.gov/vitalsigns/alcohol-screening-counseling/index.html.. Accessed: January 16, 214.
Fleming MF, Barry KL, Manwell LB, et al. Brief physician advice for problem alcohol drinkers: A randomized controlled trial in community-based primary care practices. JAMA. 1997. 277:1039-1045. [Medline].
Garbutt JC, Kranzler HR, O'Malley SS. Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial. JAMA. 2005 Apr 6. 293(13):1617-25. [Medline].
Heinz A, Reimold M, Wrase J, et al. Correlation of stable elevations in striatal {micro}-opioid receptor availability in detoxified alcoholic patients with alcohol craving: a positron emission tomography study using carbon 11-labeled carfentanil. Arch Gen Psychiatry. 2005 Jan. 62(1):57-64. [Medline].
Holahan CJ, Schutte KK, Brennan PL, et al. Episodic Heavy Drinking and 20-Year Total Mortality Among Late-Life Moderate Drinkers. Alcohol Clin Exp Res. 2014 Mar 3. [Medline].
Kiefer F, Jahn H, Tarnaske T, et al. Comparing and combining naltrexone and acamprosate in relapse prevention of alcoholism: a double-blind, placebo-controlled study. Arch Gen Psychiatry. 2003 Jan. 60(1):92-9. [Medline].
Malone SM, Iacono WG, McGue M. Drinks of the father: father's maximum number of drinks consumed predicts externalizing disorders, substance use, and substance use disorders in preadolescent and adolescent offspring. Alcohol Clin Exp Res. 2002 Dec. 26(12):1823-32. [Medline].
Mayo-Smith MF, American Society of Addiction Medicine Working Group on Pharmacology. Pharmacological management of alcohol withdrawal: A meta-analysis and evidence-based practice guideline. JAMA. 1997. 278:144-151. [Medline].
Melville N. Confirmed: Gabapentin Improves Alcohol Dependence Outcomes. Medscape [serial online]. Available at http://www.medscape.com/viewarticle/817472. Accessed: December 16, 2013.
Mendelson JH, Mello NK. Medical Diagnosis and Treatment of Alcoholism. New York, NY: McGraw-Hill; 1992.
National Institute on Alcohol Abuse and Alcoholism. Etiology and Natural History of Alcoholism. [Full Text].
NIAAA. Alcohol Involvement in Accidental Death, Homicide, and Suicide. [Full Text].
O'Connor PG, Schottenfeld RS. Patients with alcohol problems. N Engl J Med. 1998 Feb 26. 338(9):592-602. [Medline].
O'Malley SS, Jaffe AJ, Chang G, et al. Six-month follow-up of naltrexone and psychotherapy for alcohol dependence. Arch Gen Psychiatry. 1996 Mar. 53(3):217-24. [Medline].
O'Malley SS, Rounsaville BJ, Farren C, et al. Initial and maintenance naltrexone treatment for alcohol dependence using primary care vs specialty care: a nested sequence of 3 randomized trials. Arch Intern Med. Apr 6 2005. 163(14):1695-704. [Medline].
Piccinelli M, Tessari E, Bortolomasi M, et al. Efficacy of the alcohol use disorders identification test as a screening tool for hazardous alcohol intake and related disorders in primary care: a validity study. BMJ. 1997 Feb 8. 314(7078):420-4. [Medline].
Pletcher MJ, Varosy P, Kiefe CI, et al. Alcohol consumption, binge drinking, and early coronary calcification: findings from the Coronary Artery Risk Development in Young Adults (CARDIA) Study. Am J Epidemiol. 2005 Mar 1. 161(5):423-33. [Medline].
Room R, Babor T, Rehm J. Alcohol and public health. Lancet. 2005 Feb 5. 365(9458):519-30. [Medline].
Saitz R. Clinical practice. Unhealthy alcohol use. N Engl J Med. 2005 Feb 10. 352(6):596-607. [Medline].
Saitz R, O'Malley SS. Pharmacotherapies for alcohol abuse. Withdrawal and treatment. Med Clin North Am. 1997 Jul. 81(4):881-907. [Medline].
Samet JH, Rollnick S, Barnes H. Beyond CAGE. A brief clinical approach after detection of substance abuse. Arch Intern Med. 1996 Nov 11. 156(20):2287-93. [Medline].
Sigvardsson S, Bohman M, Cloninger CR. Replication of the Stockholm Adoption Study of alcoholism. Confirmatory cross-fostering analysis. Arch Gen Psychiatry. 1996 Aug. 53(8):681-7. [Medline].
Stahre M, Roeber J, Kanny D, Brewer RD, Zhang X. Contribution of excessive alcohol consumption to deaths and years of potential life lost in the United States. Prev Chronic Dis. 2014 Jun 26. 11:E109. [Medline]. [Full Text].
Steinbauer JR, Cantor SB, Holzer CE 3rd, Volk RJ. Ethnic and sex bias in primary care screening tests for alcohol use disorders. Ann Intern Med. 1998 Sep 1. 129(5):353-62. [Medline].
Thun MJ, Peto R, Lopez AD, Monaco JH, Henley SJ, Heath CW Jr. Alcohol consumption and mortality among middle-aged and elderly U.S. adults. N Engl J Med. 1997 Dec 11. 337(24):1705-14. [Medline].
Volpicelli JR, Alterman AI, Hayashida M, O'Brien CP. Naltrexone in the treatment of alcohol dependence. Arch Gen Psychiatry. 1992 Nov. 49(11):876-80. [Medline].
Walden B, McGue M, Lacono WG, et al. Identifying shared environmental contributions to early substance use: the respective roles of peers and parents. J Abnorm Psychol. 2004 Aug. 113(3):440-50. [Medline].
Walsh DC, Hingson RW, Merrigan DM, Levenson SM, Coffman GA, Heeren T, et al. The impact of a physician's warning on recovery after alcoholism treatment. JAMA. 1992 Feb 5. 267(5):663-7. [Medline].
Wilk AI, Jensen NM, Havighurst TC. Meta-analysis of randomized control trials addressing brief interventions in heavy alcohol drinkers. J Gen Intern Med. 1997 May. 12(5):274-83. [Medline].