Schizoaffective Disorder Workup

Updated: Nov 18, 2021
  • Author: Guy E Brannon, MD; Chief Editor: David Bienenfeld, MD  more...
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Approach Considerations

Workup may include selected laboratory tests, psychological testing, diagnostic imaging (eg, computed tomography [CT] or magnetic resonance imaging [MRI]), or electroencephalography (EEG).

Laboratory studies that may be performed include the following:

  • Sequential multiple analysis

  • Complete blood count (CBC)

  • Rapid plasma reagent

  • Thyroid-stimulating hormone (TSH) level or thyroid function tests

  • Urine drug screen

  • Urine pregnancy test

  • Urinalysis

  • Lipid panel [32]

  • HIV test

The Structured Clinical Interview for DSM-5 (SCID-5) is warranted to assist with diagnosis. If the patient's neurologic findings are abnormal, performing CT or MRI to rule out any suspected intracranial pathology may be appropriate. EEG should be performed if indications are present. [33]

Histologic findings include decreased amounts of cortical gray matter and increased fluid-filled spaces.