Aspergillosis Questions & Answers

Updated: Jan 10, 2019
  • Author: Eloise M Harman, MD; Chief Editor: Guy W Soo Hoo, MD, MPH  more...
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Questions & Answers

Overview

What are the main syndromes of aspergillosis?

What are the signs and symptoms of allergic bronchopulmonary aspergillosis (ABPA)?

What are the signs and symptoms of aspergilloma?

What are the signs and symptoms of chronic necrotizing pulmonary aspergillosis (CNPA)?

What are the signs and symptoms of invasive aspergillosis?

How is allergic bronchopulmonary aspergillosis (ABPA) diagnosed?

What are the diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) in persons with cystic fibrosis (CF)?

How is aspergilloma diagnosed?

How is invasive aspergillosis and chronic necrotizing pulmonary aspergillosis (CNPA) diagnosed?

Which findings on imaging studies suggest invasive aspergillosis?

What are the treatment options for allergic bronchopulmonary aspergillosis (ABPA)?

What are treatment options for aspergilloma?

What are the treatment options for invasive aspergillosis?

What are the treatment options for chronic necrotizing pulmonary aspergillosis (CNPA)?

What is aspergillosis?

What are complications resulting from aspergillosis?

What is allergic bronchopulmonary aspergillosis (ABPA)?

What is aspergilloma?

What is chronic necrotizing pulmonary aspergillosis (CNPA)?

What is invasive aspergillosis?

What is the pathophysiology of aspergillosis?

What causes aspergillosis?

What is the prevalence of aspergillosis in the US?

What is the global incidence of aspergillosis?

Which factors affect the age distribution of aspergillosis?

What is the prognosis of aspergillosis?

What are the mortality rates for aspergillosis?

Presentation

What is the common clinical manifestation of aspergillosis?

What are the clinical manifestations of allergic bronchopulmonary aspergillosis (ABPA)?

What are the clinical manifestations of aspergilloma?

What are the clinical manifestations of chronic necrotizing pulmonary aspergillosis (CNPA)?

What are the clinical manifestations of invasive aspergillosis?

Which physical findings suggest aspergillosis?

What are the complications of aspergillosis?

DDX

What other conditions should be included in the differential diagnoses of aspergillosis?

What are the differential diagnoses for Aspergillosis?

Workup

What is the basis for lab test selection in the diagnosis of aspergillosis?

Which abnormal lab findings suggest allergic bronchopulmonary aspergillosis (ABPA)?

What are the diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) in persons with cystic fibrosis (CF)?

Which lab studies are performed in the diagnosis of invasive aspergillosis or chronic necrotizing pulmonary aspergillosis (CNPA)?

What is the role of galactomannan measurement in the diagnosis of invasive aspergillosis?

What is the role of imaging studies in the workup of aspergillosis?

What is the role of skin testing in the workup of aspergillosis?

What is the role of transthoracic needle aspiration in the workup of aspergillosis?

Which procedures may be helpful for the diagnosis of invasive aspergillosis?

Which histologic findings are characteristic of aspergillosis?

How is aspergillosis staged?

Treatment

How is aspergillosis treated?

What are the treatment options for allergic bronchopulmonary aspergillosis (ABPA)?

What are the treatment options for aspergilloma?

What are the treatment options for chronic necrotizing pulmonary aspergillosis (CNPA)?

What are the treatment options for invasive aspergillosis?

Which drugs are used in the treatment of invasive aspergillosis?

What is included in inpatient care of invasive aspergillosis?

When is transfer indicated for the management of aspergillosis?

What is the role of surgery in the treatment of allergic bronchopulmonary aspergillosis (ABPA)?

What is the role of surgery in the treatment of aspergilloma?

What is the role of surgery in the treatment of chronic necrotizing pulmonary aspergillosis (CNPA) and invasive aspergillosis?

Which medical personnel provide consultation to patients with aspergillosis?

How is invasive aspergillosis prevented?

What are the indications of prophylactic antifungal therapy for the prevention of aspergillosis?

What is included in long-term monitoring of patients with aspergillosis?

Guidelines

What are the Infectious Diseases Society of America (IDSA) treatment guidelines for aspergillosis?

What are the ESCMID, ECMM, and ERS joint clinical guidelines for the diagnosis of aspergillosis?

What are the ESCMID, ECMM, and ERS joint clinical guidelines for the treatment of aspergillosis?

What are the ESCMID, ECMM, and ERS joint clinical guidelines for prophylaxis against aspergillosis?

Medications

What is the role of medications in the treatment of aspergillosis?

Which medications in the drug class Corticosteroids are used in the treatment of Aspergillosis?

Which medications in the drug class Antifungal agents are used in the treatment of Aspergillosis?