Histoplasmosis Questions & Answers

Updated: Sep 15, 2020
  • Author: Jazeela Fayyaz, DO; Chief Editor: Zab Mosenifar, MD, FACP, FCCP  more...
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Questions & Answers

Overview

What is histoplasmosis?

What are the features of histoplasmosis?

What is the pathophysiology of histoplasmosis?

What causes histoplasmosis?

What is the incidence of histoplasmosis in the US?

What is the global incidence of histoplasmosis?

What are the sexual predilections in the prevalence of histoplasmosis?

Which age groups have the highest prevalence of histoplasmosis?

What is the prognosis of histoplasmosis?

What is the mortality and morbidity associated with histoplasmosis?

What should be included in patient education about histoplasmosis?

Presentation

Which clinical history findings are characteristic of histoplasmosis?

What is the signs and symptoms of acute and subacute pulmonary histoplasmosis?

What are the signs and symptoms of chronic pulmonary histoplasmosis?

What are the signs and symptoms of progressive disseminated histoplasmosis?

What are the signs and symptoms of ocular histoplasmosis syndrome?

What are the signs and symptoms of mediastinitis in histoplasmosis?

Which physical findings are characteristic of histoplasmosis?

Which physical findings are characteristic of acute pulmonary histoplasmosis?

Which physical findings are characteristic of chronic pulmonary histoplasmosis?

Which physical findings are characteristic of chronic progressive disseminated histoplasmosis?

Which physical findings are characteristic of subacute progressive disseminated histoplasmosis?

Which physical findings are characteristic of acute progressive disseminated histoplasmosis?

Which physical findings are characteristic of presumed ocular histoplasmosis syndrome?

What are complications of histoplasmosis?

DDX

Which conditions should be included in the differential diagnoses of histoplasmosis?

What are the differential diagnoses for Histoplasmosis?

Workup

What is the role of complete blood count in the diagnosis of histoplasmosis?

What is the role of alkaline phosphatase and lactate dehydrogenase testing in the diagnosis of histoplasmosis?

What is the role of sputum cultures in the diagnosis of histoplasmosis?

What is the role of blood cultures in the diagnosis of histoplasmosis?

What is the role of complement-fixing antibody testing in the diagnosis of histoplasmosis?

What is the role of immunoprecipitating antibody testing in the diagnosis of histoplasmosis?

What is the role of serum and urine antigen detection in the diagnosis of histoplasmosis?

What is the role of chest radiography in the diagnosis of histoplasmosis?

What is the role of CT scanning in the diagnosis of histoplasmosis?

What is the role of echocardiography in the diagnosis of histoplasmosis?

What is the role of pulmonary function testing in the diagnosis of histoplasmosis?

Which clinical procedures may be performed in the diagnosis of histoplasmosis?

Which histologic findings are characteristic of histoplasmosis?

Treatment

How is histoplasmosis treated?

What is included in the medical care for acute pulmonary histoplasmosis?

What is included in the medical care for chronic pulmonary histoplasmosis?

What is included in the medical care for progressive disseminated histoplasmosis and meningitis?

What is included in the medical care for cutaneous and rheumatologic histoplasmosis?

How is broncholithiasis managed in patients with histoplasmosis?

What is included in the medical care for ocular histoplasmosis?

What is included in the medical care for mediastinal histoplasmosis?

What is the role of surgery in the treatment of histoplasmosis?

What is the role of thoracic surgery in the treatment of histoplasmosis?

What is the role of cardiac surgery in the treatment of histoplasmosis?

What is the role of laser photocoagulation in the treatment of histoplasmosis?

When is inpatient care indicated for the treatment of acute pulmonary histoplasmosis?

When is inpatient care indicated for the treatment of chronic pulmonary histoplasmosis?

When is inpatient care indicated for the treatment of progressive disseminated histoplasmosis?

When is intensive care monitoring indicated in the treatment of histoplasmosis?

When is bronchoscopy indicated in the management of histoplasmosis?

What is the role of surgery in the emergent treatment of histoplasmosis?

Which specialist consultations are beneficial for patients with histoplasmosis?

How is histoplasmosis prevented?

Which patients with histoplasmosis require long-term monitoring?

What is included in long-term monitoring following treatment for chronic pulmonary histoplasmosis?

What is included in long-term monitoring following treatment for progressive disseminated histoplasmosis?

What is included in long-term monitoring following treatment for presumed ocular histoplasmosis?

Medications

What is the goal of drug treatment for histoplasmosis?

Which antifungal medications are used in the treatment of histoplasmosis?

What is the drug of choice for the treatment of acute pulmonary histoplasmosis?

Which medications are used in the treatment of histoplasmosis?

Which medications in the drug class Corticosteroids are used in the treatment of Histoplasmosis?

Which medications in the drug class Nonsteroidal Anti-inflammatory Drugs are used in the treatment of Histoplasmosis?

Which medications in the drug class Antifungals are used in the treatment of Histoplasmosis?