Respiratory Acidosis Questions & Answers

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3. Hopkins E, Sanvictores T, Sharma S. Physiology, Acid Base Balance. StatPearls. 2021 Jan. [QxMD MEDLINE Link]. [Full Text].

4. Castro D, Keenaghan M. Arterial Blood Gas. StatPearls. 2018 Jan. [QxMD MEDLINE Link]. [Full Text].

5. Adnet F, Plaisance P, Borron SW, Levy A, Payen D. Prolonged severe hypercapnia complicating near fatal asthma in a 35-year-old woman. Intensive Care Med. 1998 Dec. 24(12):1335-8. [QxMD MEDLINE Link].

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8. Karagiannidis C, Merten ML, Heunks L, et al. Respiratory acidosis during bronchoscopy-guided percutaneous dilatational tracheostomy: impact of ventilator settings and endotracheal tube size. BMC Anesthesiol. 2019 Aug 9. 19 (1):147. [QxMD MEDLINE Link]. [Full Text].

9. Kallet RH. A Comprehensive Review of Prone Position in ARDS. Respir Care. 2015 Nov. 60 (11):1660-87. [QxMD MEDLINE Link]. [Full Text].

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11. Kellum JA. Determinants of plasma acid-base balance. Crit Care Clin. 2005 Apr. 21(2):329-46. [QxMD MEDLINE Link].

12. Ehrsam RE, Heigenhauser GJ, Jones NL. Effect of respiratory acidosis on metabolism in exercise. J Appl Physiol. 1982 Jul. 53(1):63-9. [QxMD MEDLINE Link].

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16. Pollock JM, Deibler AR, Whitlow CT, et al. Hypercapnia-Induced Cerebral Hyperperfusion: An Underrecognized Clinical Entity. AJNR Am J Neuroradiol. 2008 Oct 14. [QxMD MEDLINE Link].

17. Lun CT, Tsui MS, Cheng SL, et al. Differences in baseline factors and survival between normocapnia, compensated respiratory acidosis and decompensated respiratory acidosis in COPD exacerbation: A pilot study. Respirology. 2016 Jan. 21 (1):128-36. [QxMD MEDLINE Link].

18. de Miguel-Diez J, Jimenez-Garcia R, Hernandez-Barrera V, et al. Readmissions following an initial hospitalization by COPD exacerbation in Spain from 2006 to 2012. Respirology. 2016 Apr. 21 (3):489-96. [QxMD MEDLINE Link].

19. Fazekas AS, Aboulghaith M, Kriz RC, et al. Long-term outcomes after acute hypercapnic COPD exacerbation : First-ever episode of non-invasive ventilation. Wien Klin Wochenschr. 2018 Jul 31. [QxMD MEDLINE Link].

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21. Mochizuki K, Fujii T, Paul E, et al. Acidemia subtypes in critically ill patients: An international cohort study. J Crit Care. 2021 Aug. 64:10-7. [QxMD MEDLINE Link].

22. Sadot E, Gut G, Sivan Y. Alveolar ventilation in children during flexible bronchoscopy. Pediatr Pulmonol. 2016 Apr 8. [QxMD MEDLINE Link].

23. Saunders R, Struys MMRF, Pollock RF, Mestek M, Lightdale JR. Patient safety during procedural sedation using capnography monitoring: a systematic review and meta-analysis. BMJ Open. 2017 Jun 30. 7 (6):e013402. [QxMD MEDLINE Link]. [Full Text].

24. Wu JY, Kuo PH, Fan PC, Wu HD, Shih FY, Yang PC. The Role of Non-invasive Ventilation and Factors Predicting Extubation Outcome in Myasthenic Crisis. Neurocrit Care. 2009. 10(1):35-42. [QxMD MEDLINE Link].

25. Zhang WB, Wang XY, Tian XY, Zhang H, Wang ZP, Gao YY. [Clinical value of noninvasive positive-pressure ventilation in chronic obstruction pulmonary disease combined with type II respiratory failure: a 4-year retrospective study]. Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2008 Oct. 20(10):601-3. [QxMD MEDLINE Link].

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27. Nentwich J, Wichmann D, Kluge S, Lindau S, Mutlak H, John S. Low-flow CO₂ removal in combination with renal replacement therapy effectively reduces ventilation requirements in hypercapnic patients: a pilot study. Ann Intensive Care. 2019 Jan 7. 9 (1):3. [QxMD MEDLINE Link]. [Full Text].

28. Terragni PP, Birocco A, Faggiano C, Ranieri VM. Extracorporeal CO(2) Removal. Contrib Nephrol. 2010 April 20. 165:185-196. [QxMD MEDLINE Link]. [Full Text].

Nazir A Lone, MD, MBBS, MPH, FACP, FCCP Physician in Pulmonary and Critical Care Medicine, Peconic Bay Medical Center, Northwell Health

Nazir A Lone, MD, MBBS, MPH, FACP, FCCP is a member of the following medical societies: American Association for Bronchology and Interventional Pulmonology, American College of Chest Physicians, American College of Physicians, International Association for the Study of Lung Cancer, Medical Society of the State of New York, Society of Critical Care Medicine

Disclosure: Nothing to disclose.

Nancy W Bethuel, MD Resident Physician, Department of Internal Medicine, Basset Medical Center

Nancy W Bethuel, MD is a member of the following medical societies: American College of Physicians, American Medical Association

Disclosure: Nothing to disclose.

Laurel Whitney MD Candidate, Columbia University College of Physicians and Surgeons

Disclosure: Nothing to disclose.

Zab Mosenifar, MD, FACP, FCCP Geri and Richard Brawerman Chair in Pulmonary and Critical Care Medicine, Professor and Executive Vice Chairman, Department of Medicine, Medical Director, Women's Guild Lung Institute, Cedars Sinai Medical Center, University of California, Los Angeles, David Geffen School of Medicine

Zab Mosenifar, MD, FACP, FCCP is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Federation for Medical Research, American Thoracic Society

Disclosure: Nothing to disclose.

Ryland P Byrd, Jr, MD Professor of Medicine, Division of Pulmonary Disease and Critical Care Medicine, James H Quillen College of Medicine, East Tennessee State University

Ryland P Byrd, Jr, MD is a member of the following medical societies: American College of Chest Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

Thomas M Roy, MD Chief, Division of Pulmonary Disease and Critical Care Medicine, Quillen Mountain Home Veterans Affairs Medical Center; Professor of Medicine, Division of Pulmonary Disease and Critical Care Medicine, Fellowship Program Director, James H Quillen College of Medicine, East Tennessee State University

Thomas M Roy, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Medical Association, American Thoracic Society, Southern Medical Association, Wilderness Medical Society

Disclosure: Nothing to disclose.

Wael El Minaoui, MBBS Fellow in Pulmonary/Critical Care Medicine, East Tennessee State University, James H Quillen College of Medicine

Disclosure: Nothing to disclose.

Jackie A Hayes, MD, FCCP Clinical Assistant Professor of Medicine, University of Texas Health Science Center at San Antonio; Chief, Pulmonary and Critical Care Medicine, Department of Medicine, Brooke Army Medical Center

Jackie A Hayes, MD, FCCP is a member of the following medical societies: Alpha Omega Alpha, American College of Chest Physicians, American College of Physicians, and American Thoracic Society

Disclosure: Nothing to disclose.

Oleh Wasyl Hnatiuk, MD Program Director, National Capital Consortium, Pulmonary and Critical Care, Walter Reed Army Medical Center; Associate Professor, Department of Medicine, Uniformed Services University of Health Sciences

Oleh Wasyl Hnatiuk, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, and American Thoracic Society

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Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

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