Respiratory Alkalosis Questions & Answers

1. Brinkman JE, Sharma S. Respiratory Alkalosis. StatPearls. 2022 Jan. [QxMD MEDLINE Link]. [Full Text].

2. Hopkins E, Sanvictores T, Sharma S. Physiology, Acid Base Balance. StatPearls. 2022 Jan. [QxMD MEDLINE Link]. [Full Text].

3. Kazmaier S, Weyland A, Buhre W, et al. Effects of respiratory alkalosis and acidosis on myocardial blood flow and metabolism in patients with coronary artery disease. Anesthesiology. 1998 Oct. 89(4):831-7. [QxMD MEDLINE Link].

4. Effros RM, Wesson JA. Acid-Base Balance. Mason RJ, Broaddus VC, Murray JF, Nadel JA, eds. Murray and Nadel's Textbook of Respiratory Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005. Vol 1: 192-93.

5. DuBose TD, Jr. Acidosis and Alkalosis. Kasper DL, Braunwald E, Fauci AS, Hauser Sl, Longo DL, Jameson JL,eds. Harrison's Principles of Internal Medicine. 16th. New York, NY: McGraw-Hill; 2005. 270-1.

6. Morel J, Gergele L, Domine A, et al. The venous-arterial difference in CO₂ should be interpreted with caution in case of respiratory alkalosis in healthy volunteers. J Clin Monit Comput. 2016 Jun 10. [QxMD MEDLINE Link].

7. Hamdi H, Hassanian-Moghaddam H, Hamdi A, Zahed NS. Acid-base disturbances in acute poisoning and their association with survival. J Crit Care. 2016 Oct. 35:84-9. [QxMD MEDLINE Link].

8. Lewis JM, Fontrier TH, Coley JL. Respiratory alkalosis may impair the production of vitamin D and lead to significant morbidity, including the fibromyalgia syndrome. Med Hypotheses. 2017 May. 102:99-101. [QxMD MEDLINE Link].

9. Park JJ, Choi DJ, Yoon CH, et al. The prognostic value of arterial blood gas analysis in high-risk acute heart failure patients: an analysis of the Korean Heart Failure (KorHF) registry. Eur J Heart Fail. 2015 Jun. 17 (6):601-11. [QxMD MEDLINE Link].

10. Raphael KL, Murphy RA, Shlipak MG, et al. Bicarbonate Concentration, Acid-Base Status, and Mortality in the Health, Aging, and Body Composition Study. Clin J Am Soc Nephrol. 2016 Feb 5. 11 (2):308-16. [QxMD MEDLINE Link].

11. Phillipson EA, Duffin J. Hypoventilation and Hyperventilation Syndromes. Mason RJ, Broaddus VC, Murray JF, Nadel JA, eds. Murray and Nadel's Textbook of Respiratory Medicine. 4th ed. Philadelphia, PA: Elsevier Saunders; 2005. Vol 2: 2069-70, 2080-84.

12. Goldman A. Clinical tetany by forced respiration. JAMA. 1922. 78:1193-95.

13. Haldane JS, Poulton EP. The effects of want of oxygen on respiration. J Physiol. 1908. 37:390-407.

14. Lewis JM, Fontrier TH, Coley JL. Respiratory alkalosis may impair the production of vitamin D and lead to significant morbidity, including the fibromyalgia syndrome. Med Hypotheses. 2017 May. 102:99-101. [QxMD MEDLINE Link].

15. Kirsch DB, Jozefowicz RF. Neurologic complications of respiratory disease. Neurol Clin. 2002 Feb. 20(1):247-64, viii. [QxMD MEDLINE Link].

16. Gardner WN. The pathophysiology of hyperventilation disorders. Chest. 1996 Feb. 109(2):516-34. [QxMD MEDLINE Link].

17. Wu C, Wang G, Zhang Q, et al. Association Between Respiratory Alkalosis and the Prognosis of COVID-19 Patients. Front Med (Lausanne). 2021. 8:564635. [QxMD MEDLINE Link]. [Full Text].

Ranjodh Singh Gill, MD, FACP, CCD Professor of Internal Medicine and Surgery/Endocrinology, Central Virginia VA Health Care System, Virginia Commonwealth University School of Medicine

Ranjodh Singh Gill, MD, FACP, CCD is a member of the following medical societies: American Association of Physicians of Indian Origin, American College of Physicians, Endocrine Society, International Society for Clinical Densitometry, Medical Society of Virginia, North American Sikh Medical and Dental Association, Richmond Academy of Medicine

Disclosure: Nothing to disclose.

Francisco Talavera, PharmD, PhD Adjunct Assistant Professor, University of Nebraska Medical Center College of Pharmacy; Editor-in-Chief, Medscape Drug Reference

Disclosure: Received salary from Medscape for employment. for: Medscape.

Zab Mosenifar, MD, FACP, FCCP Geri and Richard Brawerman Chair in Pulmonary and Critical Care Medicine, Professor and Executive Vice Chairman, Department of Medicine, Medical Director, Women's Guild Lung Institute, Cedars Sinai Medical Center, University of California, Los Angeles, David Geffen School of Medicine

Zab Mosenifar, MD, FACP, FCCP is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, American Federation for Medical Research, American Thoracic Society

Disclosure: Nothing to disclose.

Ryland P Byrd, Jr, MD Professor of Medicine, Division of Pulmonary Disease and Critical Care Medicine, James H Quillen College of Medicine, East Tennessee State University

Ryland P Byrd, Jr, MD is a member of the following medical societies: American College of Chest Physicians, American Thoracic Society

Disclosure: Nothing to disclose.

Gregg T Anders, DO Medical Director, Great Plains Regional Medical Command , Brooke Army Medical Center; Clinical Associate Professor, Department of Internal Medicine, Division of Pulmonary Disease, University of Texas Health Science Center at San Antonio

Disclosure: Nothing to disclose.

Jackie A Hayes, MD, FCCP Clinical Assistant Professor of Medicine, University of Texas Health Science Center at San Antonio; Chief, Pulmonary and Critical Care Medicine, Department of Medicine, Brooke Army Medical Center

Jackie A Hayes is a member of the following medical societies: Alpha Omega Alpha, American College of Chest Physicians, American College of Physicians, and American Thoracic Society

Disclosure: Nothing to disclose.

Oleh Wasyl Hnatiuk, MD Program Director, National Capital Consortium, Pulmonary and Critical Care, Walter Reed Army Medical Center; Associate Professor, Department of Medicine, Uniformed Services University of Health Sciences

Oleh Wasyl Hnatiuk, MD is a member of the following medical societies: American College of Chest Physicians, American College of Physicians, and American Thoracic Society

Disclosure: Nothing to disclose.

April Lambert-Drwiega, DO Fellow, Department of Pulmonology and Critical Care Medicine, East Tennessee State University

April Lambert-Drwiega is a member of the following medical societies: American College of Physicians, American Medical Association, American Osteopathic Association, and Southern Medical Association

Disclosure: Nothing to disclose.

• Print this section
• Print the entire contents of
• Print the entire contents of article